| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-2B adrenergic receptor |
|---|
| Ligand | BDBM50027502 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 2630.27±n/a nM |
|---|
| Comments | PDSP_2770 |
|---|
| Citation |  Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM Ligand efficacy and potency at recombinant alpha2 adrenergic receptors: agonist-mediated [35S]GTPgammaS binding. Biochem Pharmacol55:1035-43 (1998) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Alpha-2B adrenergic receptor |
|---|
| Name: | Alpha-2B adrenergic receptor |
|---|
| Synonyms: | ADA2B_HUMAN | ADRA2B | ADRA2L1 | ADRA2RL1 | Adrenergic alpha2B | Adrenergic receptor | Adrenergic receptor alpha | Adrenergic, alpha-2B-, receptor [Homo sapiens] | Alpha-2 adrenergic receptor subtype C2 | Alpha-2B adrenoceptor | Alpha-2B adrenoreceptor | Alpha-2BAR |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 49964.20 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P18089 |
|---|
| Residue: | 450 |
|---|
| Sequence: | MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADIL
VATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEY
NSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGS
FFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESKQPRPDHGGALASAKLPALASV
ASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEE
EEEEEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGRGVGAIGGQWWRRR
AQLTREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSS
LNPVIYTIFNQDFRRAFRRILCRPWTQTAW
|
|
|
|---|
| BDBM50027502 |
|---|
| n/a |
|---|
| Name | BDBM50027502 |
|---|
| Synonyms: | 4-(2-Amino-1-hydroxy-propyl)-benzene-1,2-diol | Aldoclor-150 | Aldoclor-250 | CHEMBL764 | METHYLNORADRENALINE | alpha-Methyl-(+)norepinephrine,(+/-) | alpha-Methyl-(+/-)norepinephrine,(+/-) | alpha-Methyl-(-)norepinephrine,(+/-) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C9H13NO3 |
|---|
| Mol. Mass. | 183.2044 |
|---|
| SMILES | CC(N)C(O)c1ccc(O)c(O)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
