| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2B |
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| Ligand | BDBM50005257 |
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| Substrate/Competitor | n/a |
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| Ki | 21.8±n/a nM |
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| Comments | PDSP_706 |
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| Citation |  Nelson, DL; Lucaites, VL; Wainscott, DB; Glennon, RA Comparisons of hallucinogenic phenylisopropylamine binding affinities at cloned human 5-HT2A, -HT(2B) and 5-HT2C receptors. Naunyn Schmiedebergs Arch Pharmacol359:1-6 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 2B |
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| Name: | 5-hydroxytryptamine receptor 2B |
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| Synonyms: | 5-HT2B | 5-hydroxytryptamine receptor 2B | 5HT2B_RAT | Htr2b | Serotonin 2b (5-HT2b) receptor | Serotonin receptor 2a and 2b (5HT2A and 5HT2B) | Srl |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 53668.47 |
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| Organism: | RAT |
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| Description: | 5-HT2B HTR2B RAT::P30994 |
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| Residue: | 479 |
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| Sequence: | MASSYKMSEQSTISEHILQKTCDHLILTDRSGLKAESAAEEMKQTAENQGNTVHWAALLI
FAVIIPTIGGNILVILAVSLEKRLQYATNYFLMSLAVADLLVGLFVMPIALLTIMFEATW
PLPLALCPAWLFLDVLFSTASIMHLCAISLDRYIAIKKPIQANQCNSRTTAFVKITVVWL
ISIGIAIPVPIKGIEADVVNAHNITCELTKDRFGSFMLFGSLAAFFAPLTIMIVTYFLTI
HALRKKAYLVRNRPPQRLTRWTVSTVLQREDSSFSSPEKMVMLDGSHKDKILPNSTDETL
MRRMSSAGKKPAQTISNEQRASKVLGIVFLFFLLMWCPFFITNVTLALCDSCNQTTLKTL
LQIFVWVGYVSSGVNPLIYTLFNKTFREAFGRYITCNYQATKSVKVLRKCSSTLYFGNSM
VENSKFFTKHGIRNGINPAMYQSPVRLRSSTIQSSSIILLNTFLTENDGDKVEDQVSYI
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| BDBM50005257 |
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| n/a |
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| Name | BDBM50005257 |
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| Synonyms: | (+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine | (+)2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine | (+/-)2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine | (-)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine | (-)2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine | 1-(4-bromo-2,5-dimethoxyphenyl)propan-2-amine | 2-(2-Methoxy-phenyl)-1-methyl-ethylamine | 2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine | 2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine((-)-DOB) | 2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine((R)-(-)-DOB) | 2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine((S)-(+)-DOB) | 2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine(DOB) | 2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine[R(-)DOB] | 2-(5-Bromo-2,4-dimethoxy-phenyl)-1-methyl-ethylamine | Brolamfetamine | CHEMBL6607 | DOB | Racemic DOB |
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| Type | Small organic molecule |
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| Emp. Form. | C11H16BrNO2 |
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| Mol. Mass. | 274.154 |
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| SMILES | COc1cc(CC(C)N)c(OC)cc1Br |
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| Structure | 
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