| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2C |
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| Ligand | BDBM50240797 |
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| Substrate/Competitor | n/a |
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| Ki | 1000±n/a nM |
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| Comments | PDSP_2067 |
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| Citation |  Millan, MJ; Gobert, A; Newman-Tancredi, A; Lejeune, F; Cussac, D; Rivet, JM; Audinot, V; Dubuffet, T; Lavielle, G S33084, a novel, potent, selective, and competitive antagonist at dopamine D(3)-receptors: I. Receptorial, electrophysiological and neurochemical profile compared with GR218,231 and L741,626. J Pharmacol Exp Ther293:1048-62 (2000) [PubMed] |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 2C |
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| Name: | 5-hydroxytryptamine receptor 2C |
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| Synonyms: | 5-HT-1C | 5-HT-2C | 5-HT1C | 5-HT2C | 5-HT2C-INI | 5-HT2c VGI | 5-HTR2C | 5-hydroxytryptamine receptor 1C | 5-hydroxytryptamine receptor 2C (5-HT-2C) | 5-hydroxytryptamine receptor 2C (5HT-2C) | 5HT-1C | 5HT2C_HUMAN | HTR1C | HTR2C | Serotonin (5-HT3) receptor | Serotonin 2c (5-HT2c) receptor | Serotonin Receptor 2C |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 51836.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P28335 |
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| Residue: | 458 |
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| Sequence: | MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSI
VIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVW
PLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWA
ISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYV
LRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTM
QAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVC
SGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTN
EPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV
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| BDBM50240797 |
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| n/a |
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| Name | BDBM50240797 |
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| Synonyms: | 6-((4-methoxyphenylsulfonyl)methyl)-N,N-dipropyl-1,2,3,4-tetrahydronaphthalen-2-amine | CHEMBL334529 | GR-218231 | GR218231 | [6-(4-Methoxy-benzenesulfonylmethyl)-1,2,3,4-tetrahydro-naphthalen-2-yl]-dipropyl-amine |
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| Type | Small organic molecule |
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| Emp. Form. | C24H33NO3S |
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| Mol. Mass. | 415.589 |
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| SMILES | CCCN(CCC)C1CCc2cc(CS(=O)(=O)c3ccc(OC)cc3)ccc2C1 |
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| Structure | 
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