| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sodium-dependent dopamine transporter |
|---|
| Ligand | BDBM85704 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 3940±n/a nM |
|---|
| Comments | PDSP_7466 |
|---|
| Citation |  Rothman, RB; Baumann, MH; Dersch, CM; Romero, DV; Rice, KC; Carroll, FI; Partilla, JS Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin. Synapse39:32-41 (2001) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Sodium-dependent dopamine transporter |
|---|
| Name: | Sodium-dependent dopamine transporter |
|---|
| Synonyms: | DA transporter | Monoamine transporters; Norepininephrine & dopamine | SC6A3_RAT | Slc6a3 | Sodium-dependent dopamine transporter | Sodium-dependent dopamine transporter (DAT) |
|---|
| Type: | Multi-pass membrane protein |
|---|
| Mol. Mass.: | 68749.45 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | P23977 |
|---|
| Residue: | 619 |
|---|
| Sequence: | MSKSKCSVGPMSSVVAPAKESNAVGPREVELILVKEQNGVQLTNSTLINPPQTPVEAQER
ETWSKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELAL
GQFNREGAAGVWKICPVLKGVGFTVILISFYVGFFYNVIIAWALHYFFSSFTMDLPWIHC
NNTWNSPNCSDAHASNSSDGLGLNDTFGTTPAAEYFERGVLHLHQSRGIDDLGPPRWQLT
ACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAMDGIRAYLSVD
FYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIITTSINSLTSFSSG
FVVFSFLGYMAQKHNVPIRDVATDGPGLIFIIYPEAIATLPLSSAWAAVFFLMLLTLGID
SAMGGMESVITGLVDEFQLLHRHRELFTLGIVLATFLLSLFCVTNGGIYVFTLLDHFAAG
TSILFGVLIEAIGVAWFYGVQQFSDDIKQMTGQRPNLYWRLCWKLVSPCFLLYVVVVSIV
TFRPPHYGAYIFPDWANALGWIIATSSMAMVPIYATYKFCSLPGSFREKLAYAITPEKDH
QLVDRGEVRQFTLRHWLLL
|
|
|
|---|
| BDBM85704 |
|---|
| n/a |
|---|
| Name | BDBM85704 |
|---|
| Synonyms: | CAS_461-78-9 | Chlorphentermine | NSC_10007 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H14ClN |
|---|
| Mol. Mass. | 183.678 |
|---|
| SMILES | CC(C)(N)Cc1ccc(Cl)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
