| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosinase |
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| Ligand | BDBM50218205 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| pH | 6.8±0 |
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| Temperature | 310.15±0 K |
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| IC50 | 2.994e+4± 428.89 nM |
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| Citation |  Khan, KM; Saify, ZS; Khan, MT; Butt, N; Maharvi, GM; Perveen, S; Ambreen, N; Choudhary, MI; Atta-Ur-Rahman, A; Supuran, CT Tyrosinase inhibition: conformational analysis based studies on molecular dynamics calculations of bipiperidine based inhibitors. J Enzyme Inhib Med Chem20:401-7 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Tyrosinase |
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| Name: | Tyrosinase |
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| Synonyms: | LB24-AB | Monophenol monooxygenase | SK29-AB | TYR | TYRO_HUMAN | Tumor rejection antigen AB |
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| Type: | Protein |
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| Mol. Mass.: | 60388.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14679 |
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| Residue: | 529 |
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| Sequence: | MLLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRSPCGQLSGRGSCQNILL
SNAPLGPQFPFTGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFWGPNCTERRLLVR
RNIFDLSAPEKDKFFAYLTLAKHTISSDYVIPIGTYGQMKNGSTPMFNDINIYDLFVWMH
YYVSMDALLGGSEIWRDIDFAHEAPAFLPWHRLFLLRWEQEIQKLTGDENFTIPYWDWRD
AEKCDICTDEYMGGQHPTNPNLLSPASFFSSWQIVCSRLEEYNSHQSLCNGTPEGPLRRN
PGNHDKSRTPRLPSSADVEFCLSLTQYESGSMDKAANFSFRNTLEGFASPLTGIADASQS
SMHNALHIYMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLQEVYPEANAPIGH
NRESYMVPFIPLYRNGDFFISSKDLGYDYSYLQDSDPDSFQDYIKSYLEQASRIWSWLLG
AAMVGAVLTALLAGLVSLLCRHKRKQLPEEKQPLLMEKEDYHSLYQSHL
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| BDBM50218205 |
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| n/a |
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| Name | BDBM50218205 |
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| Synonyms: | 1-(4-(piperidin-1-yl)piperidin-1-yl)ethanone | CHEMBL249343 | Tyrosinase Inhibitor, 2 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H22N2O |
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| Mol. Mass. | 210.3159 |
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| SMILES | CC(=O)N1CCC(CC1)N1CCCCC1 |
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| Structure | 
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