Reaction Details |
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Target | Delta-type opioid receptor |
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Ligand | BDBM85944 |
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Substrate/Competitor | n/a |
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Ki | 304±n/a nM |
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Comments | PDSP_2348 |
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Citation | Martin, NA; Ruckle, MB; VanHoof, SL; Prather, PL Agonist, antagonist, and inverse agonist characteristics of TIPP (H-Tyr-Tic-Phe-Phe-OH), a selective delta-opioid receptor ligand. J Pharmacol Exp Ther301:661-71 (2002) [PubMed] Article |
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More Info.: | Get all data from this article |
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Delta-type opioid receptor |
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Name: | Delta-type opioid receptor |
Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40382.98 |
Organism: | Homo sapiens (Human) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
Residue: | 372 |
Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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BDBM85944 |
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n/a |
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Name | BDBM85944 |
Synonyms: | CAS_107691 | ICI-174864 | NSC_107691 |
Type | Small organic molecule |
Emp. Form. | C34H46N4O6 |
Mol. Mass. | 606.7522 |
SMILES | CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)C(C)(C)NC(=O)C(Cc1ccc(O)cc1)N(CC=C)CC=C)C(O)=O |
Structure |
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