| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor A |
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| Ligand | BDBM50287290 |
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| Substrate/Competitor | n/a |
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| Ki | 1.02±n/a nM |
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| Comments | PDSP_3385 |
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| Citation |  Inada, Y; Nakane, T; Chiba, S Binding of KRH-594, an antagonist of the angiotensin II type 1 receptor, to cloned human and rat angiotensin II receptors. Fundam Clin Pharmacol16:317-23 (2002) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Type-1 angiotensin II receptor A |
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| Name: | Type-1 angiotensin II receptor A |
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| Synonyms: | AGTRA_RAT | ANGIOTENSIN AT1 | Agtr1 | Agtr1a | Angiotensin II AT1 | Angiotensin II AT1A | Angiotensin II receptor (AT-1) type-1 | At1a | Type-1A angiotensin II receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40910.53 |
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| Organism: | RAT |
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| Description: | ANGIOTENSIN AT1 AGTR1 RAT::P25095 |
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| Residue: | 359 |
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| Sequence: | MALNSSAEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVC
AFHYESRNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFR
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCKISDIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPSDNMSSSAKKPASCFEVE
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| BDBM50287290 |
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| n/a |
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| Name | BDBM50287290 |
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| Synonyms: | CHEMBL34866 | KRH-594 | Potassium; 2-[5-ethyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-[1,3,4]thiadiazol-(2Z)-ylidenecarbamoyl]-cyclopent-1-enecarboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C25H22N7O3S |
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| Mol. Mass. | 500.553 |
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| SMILES | CCc1nn(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c(=NC(=O)C2=C(CCC2)C([O-])=O)s1 |w:24.27,t:30| |
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| Structure | 
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