Reaction Details |
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Target | Delta-type opioid receptor |
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Ligand | BDBM86546 |
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Substrate/Competitor | n/a |
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Ki | 3.4±n/a nM |
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Comments | PDSP_740 |
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Citation | Wang, Y; Tang, K; Inan, S; Siebert, D; Holzgrabe, U; Lee, DY; Huang, P; Li, JG; Cowan, A; Liu-Chen, LY Comparison of pharmacological activities of three distinct kappa ligands (Salvinorin A, TRK-820 and 3FLB) on kappa opioid receptors in vitro and their antipruritic and antinociceptive activities in vivo. J Pharmacol Exp Ther312:220-30 (2005) [PubMed] Article |
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More Info.: | Get all data from this article |
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Delta-type opioid receptor |
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Name: | Delta-type opioid receptor |
Synonyms: | DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 40577.25 |
Organism: | MOUSE |
Description: | P32300 |
Residue: | 372 |
Sequence: | MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTAC
TPSDGPGGGAAA
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BDBM86546 |
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n/a |
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Name | BDBM86546 |
Synonyms: | CAS_88373-73-3 | DPDPE | NSC_104787 |
Type | Small organic molecule |
Emp. Form. | C30H39N5O7S2 |
Mol. Mass. | 645.79 |
SMILES | CC1(C)SSC(C)(C)C(NC(=O)C(N)Cc2ccc(O)cc2)C(=O)NCC(=O)NC(Cc2ccccc2)C(=O)NC1C(O)=O |
Structure |
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