Reaction Details |
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Target | Delta-type opioid receptor |
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Ligand | BDBM86669 |
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Substrate/Competitor | n/a |
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Ki | 2.1±n/a nM |
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Comments | PDSP_4767 |
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Citation | Tryoen-Tóth, P; Décaillot, FM; Filliol, D; Befort, K; Lazarus, LH; Schiller, PW; Schmidhammer, H; Kieffer, BL Inverse agonism and neutral antagonism at wild-type and constitutively active mutant delta opioid receptors. J Pharmacol Exp Ther313:410-21 (2005) [PubMed] Article |
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More Info.: | Get all data from this article |
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Delta-type opioid receptor |
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Name: | Delta-type opioid receptor |
Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40382.98 |
Organism: | Homo sapiens (Human) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
Residue: | 372 |
Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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BDBM86669 |
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n/a |
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Name | BDBM86669 |
Synonyms: | HS414 |
Type | Small organic molecule |
Emp. Form. | C27H27N2O3 |
Mol. Mass. | 427.5149 |
SMILES | CCO[C@]12Cc3c(nc4ccccc34)C3Oc4c5c(CC1N(CC=C)CCC235)ccc4O |r,TLB:22:21:18.19.17:3,16:17:3:21.25.26,THB:2:3:18.19.17:21.25.26| |
Structure |
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