| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM86663 |
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| Substrate/Competitor | n/a |
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| Ki | 0.22±n/a nM |
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| Comments | PDSP_4771 |
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| Citation |  Tryoen-Tóth, P; Décaillot, FM; Filliol, D; Befort, K; Lazarus, LH; Schiller, PW; Schmidhammer, H; Kieffer, BL Inverse agonism and neutral antagonism at wild-type and constitutively active mutant delta opioid receptors. J Pharmacol Exp Ther313:410-21 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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| BDBM86663 |
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| n/a |
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| Name | BDBM86663 |
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| Synonyms: | CAS_0 | HS595 | NSC_0 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H29NO5 |
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| Mol. Mass. | 459.5336 |
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| SMILES | COc1c2O[C@@]3(C)c4oc5ccccc5c4C[C@@]4(O)C5Cc(cc1O)c2C34CCN5CC1CC1 |r,TLB:30:29:21.20.25:17,3:25:17:29.28.27,THB:18:17:21.20.25:29.28.27| |
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| Structure | 
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