| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
|---|
| Ligand | BDBM26739 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | >10000±n/a nM |
|---|
| Comments | PDSP_5529 |
|---|
| Citation |  Gobbi, G; Bambico, FR; Mangieri, R; Bortolato, M; Campolongo, P; Solinas, M; Cassano, T; Morgese, MG; Debonnel, G; Duranti, A; Tontini, A; Tarzia, G; Mor, M; Trezza, V; Goldberg, SR; Cuomo, V; Piomelli, D Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis. Proc Natl Acad Sci U S A102:18620-5 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Beta-1 adrenergic receptor |
|---|
| Name: | Beta-1 adrenergic receptor |
|---|
| Synonyms: | ADRB1R, B1AR | ADRB1_RAT | Adrb1 | Adrb1r | Adrenergic receptor beta | Beta-1 adrenoceptor | Beta-1 adrenoreceptor | adrenergic Beta1 | adrenergic Beta1,2 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 50486.84 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P18090 |
|---|
| Residue: | 466 |
|---|
| Sequence: | MGAGALALGASEPCNLSSAAPLPDGAATAARLLVLASPPASLLPPASEGSAPLSQQWTAG
MGLLLALIVLLIVVGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITLPFRYQSLLTRARARALVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLTGPPRPPSPAPSPSPGPPRPADSLANGRSSKRRP
SRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSA
FNPIIYCRSPDFRKAFQRLLCCARRAACRRRAAHGDRPRASGCLARAGPPPSPGAPSDDD
DDDAGATPPARLLEPWAGCNGGTTTVDSDSSLDEPGRQGFSSESKV
|
|
|
|---|
| BDBM26739 |
|---|
| n/a |
|---|
| Name | BDBM26739 |
|---|
| Synonyms: | 3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate | CHEMBL184238 | URB 597 | URB-597 | URB597 | US9187413, 1a (URB597) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H22N2O3 |
|---|
| Mol. Mass. | 338.4003 |
|---|
| SMILES | NC(=O)c1cccc(c1)-c1cccc(OC(=O)NC2CCCCC2)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
