| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
|---|
| Ligand | BDBM87020 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 243.8±n/a nM |
|---|
| Comments | PDSP_8607 |
|---|
| Citation |  Wang, H; Duffy, RA; Boykow, GC; Chackalamannil, S; Madison, VS Identification of novel cannabinoid CB1 receptor antagonists by using virtual screening with a pharmacophore model. J Med Chem51:2439-46 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Cannabinoid receptor 1 |
|---|
| Name: | Cannabinoid receptor 1 |
|---|
| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 52868.96 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21554 |
|---|
| Residue: | 472 |
|---|
| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
|
|
|
|---|
| BDBM87020 |
|---|
| n/a |
|---|
| Name | BDBM87020 |
|---|
| Synonyms: | (3R,4S)-4-(4-methoxyphenyl)-1-phenyl-3-(3-(pyridin-3-yl)propyl)azetidin-2-one | CAS_15481172 | NSC_15481172 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H24N2O2 |
|---|
| Mol. Mass. | 372.4596 |
|---|
| SMILES | COc1ccc(cc1)C1C(CCCc2cccnc2)C(=O)N1c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
