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TargetGTP-binding nuclear protein GSP1/CNR1
LigandBDBM87019
Substrate/Competitorn/a
Ki 5.8±n/a nM
CommentsPDSP_8598
Citation Wang, HDuffy, RABoykow, GCChackalamannil, SMadison, VS Identification of novel cannabinoid CB1 receptor antagonists by using virtual screening with a pharmacophore model. J Med Chem51:2439-46 (2008) [PubMed]  Article
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GTP-binding nuclear protein GSP1/CNR1
Name:GTP-binding nuclear protein GSP1/CNR1
Synonyms:CANNABINOID CB1 | CNR1 | CST17 | GSP1 | GSP1_YEAST | GTP-binding nuclear protein GSP1/CNR1
Type:Enzyme Catalytic Domain
Mol. Mass.:24810.06
Organism:Saccharomyces cerevisiae
Description:CANNABINOID CB1 CNR1 0::P32835
Residue:219
Sequence:
MSAPAANGEVPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATIGVEVHPLSFYTNFGE
IKFDVWDTAGQEKFGGLRDGYYINAQCAIIMFDVTSRITYKNVPNWHRDLVRVCENIPIV
LCGNKVDVKERKVKAKTITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLAGNPQLEFVA
SPALAPPEVQVDEQLMQQYQQEMEQATALPLPDEDDADL
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BDBM87019
n/a
NameBDBM87019
Synonyms:1-(2,4-dichlorophenyl)-4-(hydroxymethyl)-N-(piperidin-1-yl)-5-(4-(pyridin-3-yl)phenyl)-1H-pyrazole-3-carboxamide | CAS_10186399 | NSC_10186399
TypeSmall organic molecule
Emp. Form.C27H25Cl2N5O2
Mol. Mass.522.426
SMILESOCc1c(nn(c1-c1ccc(cc1)-c1cccnc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Structure
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