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TargetGTP-binding nuclear protein GSP2/CNR2
LigandBDBM50176988
Substrate/Competitorn/a
Ki 21±n/a nM
CommentsPDSP_8602
Citation Wang, HDuffy, RABoykow, GCChackalamannil, SMadison, VS Identification of novel cannabinoid CB1 receptor antagonists by using virtual screening with a pharmacophore model. J Med Chem51:2439-46 (2008) [PubMed]  Article
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GTP-binding nuclear protein GSP2/CNR2
Name:GTP-binding nuclear protein GSP2/CNR2
Synonyms:CANNABINOID CB2 | CNR2 | GSP2 | GSP2_YEAST | GTP-binding nuclear protein GSP2/CNR2
Type:Enzyme Catalytic Domain
Mol. Mass.:24990.72
Organism:Saccharomyces cerevisiae
Description:CANNABINOID CB2 CNR2 0::P32836
Residue:220
Sequence:
MSAPAQNNAEVPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATIGVEVHPLSFYTNFG
EIKFDVWDTAGQEKFGGLRDGYYINAQCAIIMFDVTSRITYKNVPNWHRDLVRVCENIPI
VLCGNKVDVKERKVKAKTITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLAGNPQLEFV
ASPALAPPEVQVDEQLMHQYQQEMDQATALPLPDEDDADL
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BDBM50176988
n/a
NameBDBM50176988
Synonyms:8-Chloro-1-(2,4-dichloro-phenyl)-1,3a,4,5,6,10b-hexahydro-1,2-diaza-benzo[e]azulene-3-carboxylic acid piperidin-1-ylamide | 8-chloro-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide | 8-chloro-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide | 8-chloro-1-(2,4-dichloro-phenyl)-1,4,5,6-tetrahydro-1,2-diaza-benzo[e]azulene-3-carboxylic acid piperidin-1-ylamide | CHEMBL376700
TypeSmall organic molecule
Emp. Form.C24H23Cl3N4O
Mol. Mass.489.825
SMILESClc1ccc(c(Cl)c1)-n1nc(C(=O)NN2CCCCC2)c2CCCc3cc(Cl)ccc3-c12
Structure
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