| Reaction Details |
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 | Report a problem with these data |
| Target | dCTP deaminase |
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| Ligand | BDBM50173540 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| pH | 8±0 |
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| Temperature | 298.15±0 K |
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| Ki | 1.000000e+9±n/a nM |
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| Citation |  Musso-Buendía, JA; Vidal, AE; Kasinthan, G; Nguyen, C; Carrero-Lérida, J; Ruiz-Pérez, LM; Wilson, K; Johansson, NG; Gilbert, IH; González-Pacanowska, D Kinetic properties and inhibition of the dimeric dUTPase-dUDPase from Campylobacter jejuni. J Enzyme Inhib Med Chem24:111-6 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| dCTP deaminase |
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| Name: | dCTP deaminase |
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| Synonyms: | DCD_CAMJE | Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) | dcd |
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| Type: | Protein |
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| Mol. Mass.: | 20698.65 |
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| Organism: | Campylobacter jejuni |
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| Description: | n/a |
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| Residue: | 186 |
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| Sequence: | MGLKADNWIRKMALEHKMIEPFCEANIGKGVVSYGLSSYGYDIRVGREFKIFTNVNSTVV
DPKNFVEENVVDFEGDVCIVPANSFALARTIEYFKMPDNVLAICLGKSTYARCGIIVNVT
PFEPGFEGHITIEISNTTPLPAKIYANEGIAQVLFLQGDEKCDTTYKDKKGKYQAQTGIT
LPRILK
|
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|
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| BDBM50173540 |
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| n/a |
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| Name | BDBM50173540 |
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| Synonyms: | 1-[5-(tert-Butyl-diphenyl-silanyloxymethyl)-2,5-dihydro-furan-2-yl]-1H-pyrimidine-2,4-dione | CHEMBL371690 | dUTPase inhibitor, 5 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H28N2O4Si |
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| Mol. Mass. | 448.5863 |
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| SMILES | CC(C)(C)[Si](OCC1OC(C=C1)n1ccc(=O)[nH]c1=O)(c1ccccc1)c1ccccc1 |c:10| |
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| Structure | 
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