| Reaction Details |
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 | Report a problem with these data |
| Target | Putative glycogen synthase kinase 3 alpha |
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| Ligand | BDBM92356 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | 4.7± 0.4 nM |
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| Citation |  Grütter, C; Simard, JR; Mayer-Wrangowski, SC; Schreier, PH; Pérez-Martín, J; Richters, A; Getlik, M; Gutbrod, O; Braun, CA; Beck, ME; Rauh, D Targeting GSK3 from Ustilago maydis: Type-II Kinase Inhibitors as Potential Antifungals. ACS Chem Biol7:1257-67 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Putative glycogen synthase kinase 3 alpha |
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| Name: | Putative glycogen synthase kinase 3 alpha |
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| Synonyms: | Glycogen Synthase Kinase 3 (GSK3) |
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| Type: | Protein |
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| Mol. Mass.: | 45420.65 |
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| Organism: | Ustilago maydis (Smut fungus) |
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| Description: | A0A0D1CGS9 |
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| Residue: | 402 |
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| Sequence: | MSNAPLNGVKLNPLDDPNKVIKVLASDGKTGEQREIAYTNCKVIGNGSFGVVFQAKLVSQ
GSEPAEGSSKESDEVAIKKVLQDKRFKNRELQIMRIVKHPNVVDLKAFFYSNGDKKDEVF
LNLVLEYVPETVYRASRHYAKLKQTMPMLLIKLYMYQLLRSLAYIHSIGICHRDIKPQNL
LLDPPSGVLKLIDFGSAKILIAGEPNVSYICSRYYRAPELIFGATNYTTNIDIWSTGCVM
AELMQGQPLFPGESGIDQLVEIIKVLGTPSREQIKTMNPNYMEHKFPQIRPHPFSKVFRP
RTPPDAIDLISRLLEYTPSARLTAIEALCHPFFDELRTGEARMPNGRELPPLFNWTKEEL
SVRPDLISRLVPQHAEAELLSRGIDVHNFQPIPLESLKVTLD
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| BDBM92356 |
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| n/a |
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| Name | BDBM92356 |
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| Synonyms: | Chir98014, 20 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H17Cl2N9O2 |
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| Mol. Mass. | 486.314 |
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| SMILES | Nc1nc(NCCNc2ncc(c(n2)-c2ccc(Cl)cc2Cl)-n2ccnc2)ccc1N(=O)=O |
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| Structure | 
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