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TargetAcetylcholine Binding protein
LigandBDBM86311
Substrate/Competitorn/a
Meas. Tech.Radioligand Competition Assay
Ki 8.2±2 nM
Citation Rohde LAAhring PKJensen MLNielsen EØPeters DHelgstrand CKrintel CHarpsøe KGajhede MKastrup JSBalle T Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine α4β2 receptors: unique role of halogen bonding revealed. J Biol Chem 287:4248-59 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Acetylcholine Binding protein
Name:Acetylcholine Binding protein
Synonyms:ACh-binding protein | Acetylcholine-binding protein | Acetylcholine-binding protein (AchBP) | Acetylcholine-binding protein (Ls-AchBP) | AchBP
Type:n/a
Mol. Mass.:26055.52
Organism:Lymnaea stagnalis
Description:Soluble acetylcholine receptor
Residue:229
Sequence:
MRRNIFCLACLWIVQACLSLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEV
NEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQ
LARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDD
SEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRSEIL
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  Blast E-value cutoff:
BDBM86311
n/a
NameBDBM86311
Synonyms:CAS_485-35-8 | Cytisine | Cytisine-(-) | NSC_22407
TypeSmall organic molecule
Emp. Form.C11H14N2O
Mol. Mass.190.2417
SMILESO=c1cccc2C3CNCC(C3)Cn12 |THB:4:5:11:9.8.7|
Structure
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