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TargetAcetylcholine Binding protein
LigandBDBM50088438
Substrate/Competitorn/a
Meas. Tech.Radioligand Competition Assay
Ki 3.1±0.9 nM
Citation Rohde LAAhring PKJensen MLNielsen EØPeters DHelgstrand CKrintel CHarpsøe KGajhede MKastrup JSBalle T Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine α4β2 receptors: unique role of halogen bonding revealed. J Biol Chem 287:4248-59 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Acetylcholine Binding protein
Name:Acetylcholine Binding protein
Synonyms:ACh-binding protein | Acetylcholine-binding protein | Acetylcholine-binding protein (AchBP) | Acetylcholine-binding protein (Ls-AchBP) | AchBP
Type:n/a
Mol. Mass.:26055.52
Organism:Lymnaea stagnalis
Description:Soluble acetylcholine receptor
Residue:229
Sequence:
MRRNIFCLACLWIVQACLSLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEV
NEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQ
LARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDD
SEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRSEIL
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  Blast E-value cutoff:
BDBM50088438
n/a
NameBDBM50088438
Synonyms:1-(pyridin-3-yl)-1,4-diazepane | 1-Pyridin-3-yl-[1,4]diazepane | CHEMBL71085 | NS3531, 1
TypeSmall organic molecule
Emp. Form.C10H15N3
Mol. Mass.177.2462
SMILESC1CNCCN(C1)c1cccnc1
Structure
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