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Target4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6
LigandBDBM50070942
Substrate/Competitorn/a
Meas. Tech.SPA Assay
pH7.3±0
Temperature295.15±0 K
IC50 1800±200 nM
Citation Niu, XFan, XSun, JTing, PNarula, SLundell, D Inhibition of fucosyltransferase VII by gallic acid and its derivatives. Arch Biochem Biophys425:51-7 (2004) [PubMed]  Article
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4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6
Name:4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6
Synonyms:Alpha-(1,3)-fucosyltransferase IV | FCT3A | FUT6 | FUT6_HUMAN | Fucosyltransferase 6 | Fucosyltransferase IV | Fuct IV
Type:n/a
Mol. Mass.:41871.43
Organism:Homo sapiens (Human)
Description:P51993
Residue:359
Sequence:
MDPLGPAKPQWSWRCCLTTLLFQLLMAVCFFSYLRVSQDDPTVYPNGSRFPDSTGTPAHS
IPLILLWTWPFNKPIALPRCSEMVPGTADCNITADRKVYPQADAVIVHHREVMYNPSAQL
PRSPRRQGQRWIWFSMESPSHCWQLKAMDGYFNLTMSYRSDSDIFTPYGWLEPWSGQPAH
PPLNLSAKTELVAWAVSNWGPNSARVRYYQSLQAHLKVDVYGRSHKPLPQGTMMETLSRY
KFYLAFENSLHPDYITEKLWRNALEAWAVPVVLGPSRSNYERFLPPDAFIHVDDFQSPKD
LARYLQELDKDHARYLSYFRWRETLRPRSFSWALAFCKACWKLQEESRYQTRGIAAWFT
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  Blast E-value cutoff:
BDBM50070942
n/a
NameBDBM50070942
Synonyms:(-)-Epigallocatechin gallate | (-)-Epigallocatechin-3-o-gallate | (-)-epigallocatechin 3-gallate | (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate | CHEMBL297453 | EGCG | Epigallocatechin 3-gallate | Epigallocatechin monogallate, B | cid_65064
TypeSmall organic molecule
Emp. Form.C22H18O11
Mol. Mass.458.3717
SMILESOc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c1cc(O)c(O)c(O)c1 |r|
Structure
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