| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cytochrome P450 2E1 |
|---|
| Ligand | BDBM92497 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Binding Assay |
|---|
| Kd | 2.1e+4±n/a nM |
|---|
| Citation |  Porubsky, PR; Battaile, KP; Scott, EE Human cytochrome P450 2E1 structures with fatty acid analogs reveal a previously unobserved binding mode. J Biol Chem285:22282-90 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cytochrome P450 2E1 |
|---|
| Name: | Cytochrome P450 2E1 |
|---|
| Synonyms: | CP2E1_HUMAN | CYP2E | CYP2E1 | Cytochrome P450 2E1 (CYP2E1) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 56860.34 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P05181 |
|---|
| Residue: | 493 |
|---|
| Sequence: | MSALGVTVALLVWAAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRL
AQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGP
TWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVI
ADILFRKHFDYNDEKFLRLMYLFNENFHLLSTPWLQLYNNFPSFLHYLPGSHRKVIKNVA
EVKEYVSERVKEHHQSLDPNCPRDLTDCLLVEMEKEKHSAERLYTMDGITVTVADLFFAG
TETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRF
ITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGK
FKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDLSPIHIGFGC
IPPRYKLCVIPRS
|
|
|
|---|
| BDBM92497 |
|---|
| n/a |
|---|
| Name | BDBM92497 |
|---|
| Synonyms: | CHEMBL542051 | Omega-imidazolyl octanoic acid |
|---|
| Type | Fatty acid |
|---|
| Emp. Form. | C11H18N2O2 |
|---|
| Mol. Mass. | 210.2728 |
|---|
| SMILES | OC(=O)CCCCCCCn1ccnc1 |
|---|
| Structure | 
|
|---|
Search and Browse
