| Reaction Details |
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 | Report a problem with these data |
| Target | EEF1AKMT4-ECE2 readthrough transcript protein |
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| Ligand | BDBM21642 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzymatic Assay |
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| Ki | >100000±0 nM |
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| IC50 | >100000±0 nM |
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| Citation |  Ouimet, T; Orng, SV; Poras, H; Gagnidze, K; Devi, LA; Fournié-Zaluski, MC; Roques, BP Identification of an endothelin-converting enzyme-2-specific fluorigenic substrate and development of an in vitro and ex vivo enzymatic assay. J Biol Chem285:34390-400 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| EEF1AKMT4-ECE2 readthrough transcript protein |
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| Name: | EEF1AKMT4-ECE2 readthrough transcript protein |
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| Synonyms: | EEF1AKMT4-ECE2 | EFCE2_HUMAN | Endothelin-converting enzyme 2 | Endothelin-converting enzyme 2 (ECE-2) | Endothelin-converting enzyme 2 (ECE2) | Endothelin-converting enzyme 2 region |
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| Type: | Enzyme |
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| Mol. Mass.: | 99745.05 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DPD8 |
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| Residue: | 883 |
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| Sequence: | MASPGAGRAPPELPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPED
RILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFP
SASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVGFQKGTRQLLGSRTQLELV
LAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQ
FSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCL
QVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSK
SSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQV
LELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPV
VVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKS
CVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDE
KTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMAD
QLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGH
ELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGE
NIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGL
VTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
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| BDBM21642 |
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| n/a |
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| Name | BDBM21642 |
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| Synonyms: | (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid | CHEMBL1560 | Capozide | Captopril | Lopirin | SQ 14,225 | SQ14534 | US11491146, Compound L-Captopril |
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| Type | Small organic molecule |
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| Emp. Form. | C9H15NO3S |
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| Mol. Mass. | 217.285 |
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| SMILES | C[C@H](CS)C(=O)N1CCC[C@H]1C(O)=O |
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| Structure | 
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