| Reaction Details |
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 | Report a problem with these data |
| Target | Macrophage migration inhibitory factor |
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| Ligand | BDBM31712 |
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| Substrate/Competitor | BDBM92519 |
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| Meas. Tech. | Tautomerase Enzyme Assay |
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| pH | 6.5±0 |
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| Ki | 5.55e+3±n/a nM |
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| IC50 | 6.00e+3±n/a nM |
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| Citation |  Ouertatani-Sakouhi, H; El-Turk, F; Fauvet, B; Cho, MK; Pinar Karpinar, D; Le Roy, D; Dewor, M; Roger, T; Bernhagen, J; Calandra, T; Zweckstetter, M; Lashuel, HA Identification and characterization of novel classes of macrophage migration inhibitory factor (MIF) inhibitors with distinct mechanisms of action. J Biol Chem285:26581-98 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Macrophage migration inhibitory factor |
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| Name: | Macrophage migration inhibitory factor |
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| Synonyms: | GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase |
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| Type: | Enzyme |
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| Mol. Mass.: | 12478.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14174 |
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| Residue: | 115 |
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| Sequence: | MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALC
SLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
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| BDBM31712 |
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| BDBM92519 |
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| Name | BDBM31712 |
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| Synonyms: | HEXACHLOROPHENE | Hexach-lorophene | MLS000028433 | SMR000058356 | cid_3598 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H6Cl6O2 |
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| Mol. Mass. | 406.904 |
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| SMILES | Oc1c(Cl)cc(Cl)c(Cl)c1Cc1c(O)c(Cl)cc(Cl)c1Cl |
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| Structure | 
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