Compile Data Set for Download or QSAR

Found 41 hits with Last Name = 'fauvet' and Initial = 'b'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM63895 (7,10-dioxo-4,5-dihydro-7H,10H-pyrano[3,2-c]pyrrolo...) Show SMILES Fc1ccc(cc1)C(=O)Oc1cc(=O)oc2c3cccc4CCn(c34)c(=O)c12 Show InChI InChI=1S/C21H12FNO5/c22-13-6-4-12(5-7-13)21(26)27-15-10-16(24)28-19-14-3-1-2-11-8-9-23(18(11)14)20(25)17(15)19/h1-7,10H,8-9H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	190	n/a	1.41E+3	n/a	n/a	n/a	n/a	6.5	n/a
Ecole Polytechnique Fédérale de Lausanne					Assay Description The assay principle is based on measuring the absorbance of D-dopachrome methyl ester (red), which is transformed by enzymatically active MIF to the ...				J Biol Chem 285: 26581-98 (2010) Article DOI: 10.1074/jbc.M110.113951 BindingDB Entry DOI: 10.7270/Q2XD1083
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM92511 (JFD 03990, 7) Show SMILES O=C(Oc1cc(=O)n(-c2ccccc2)c2ccccc12)c1ccccc1 Show InChI InChI=1S/C22H15NO3/c24-21-15-20(26-22(25)16-9-3-1-4-10-16)18-13-7-8-14-19(18)23(21)17-11-5-2-6-12-17/h1-15H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	230	n/a	1.55E+3	n/a	n/a	n/a	n/a	6.5	n/a
Ecole Polytechnique Fédérale de Lausanne					Assay Description The assay principle is based on measuring the absorbance of D-dopachrome methyl ester (red), which is transformed by enzymatically active MIF to the ...				J Biol Chem 285: 26581-98 (2010) Article DOI: 10.1074/jbc.M110.113951 BindingDB Entry DOI: 10.7270/Q2XD1083
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM92518 (RJC 04082, 14) Show SMILES O=C(Oc1cc(=O)n2CCCc3cccc1c23)c1ccccc1 Show InChI InChI=1S/C19H15NO3/c21-17-12-16(23-19(22)14-6-2-1-3-7-14)15-10-4-8-13-9-5-11-20(17)18(13)15/h1-4,6-8,10,12H,5,9,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	450	n/a	3.02E+3	n/a	n/a	n/a	n/a	6.5	n/a
Ecole Polytechnique Fédérale de Lausanne					Assay Description The assay principle is based on measuring the absorbance of D-dopachrome methyl ester (red), which is transformed by enzymatically active MIF to the ...				J Biol Chem 285: 26581-98 (2010) Article DOI: 10.1074/jbc.M110.113951 BindingDB Entry DOI: 10.7270/Q2XD1083
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM34233 (2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...) Show SMILES O=c1n([se]c2ccccc12)-c1ccccc1 Show InChI InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	570	n/a	2.40E+3	n/a	n/a	n/a	n/a	6.5	n/a
Ecole Polytechnique Fédérale de Lausanne					Assay Description The assay principle is based on measuring the absorbance of D-dopachrome methyl ester (red), which is transformed by enzymatically active MIF to the ...				J Biol Chem 285: 26581-98 (2010) Article DOI: 10.1074/jbc.M110.113951 BindingDB Entry DOI: 10.7270/Q2XD1083
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM92515 (RDR 03785, 11) Show SMILES Oc1cc2OCOc2cc1C(N1CCOCC1)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C19H18F3NO4/c20-19(21,22)13-3-1-12(2-4-13)18(23-5-7-25-8-6-23)14-9-16-17(10-15(14)24)27-11-26-16/h1-4,9-10,18,24H,5-8,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	570	n/a	2.40E+3	n/a	n/a	n/a	n/a	6.5	n/a
Ecole Polytechnique Fédérale de Lausanne					Assay Description The assay principle is based on measuring the absorbance of D-dopachrome methyl ester (red), which is transformed by enzymatically active MIF to the ...				J Biol Chem 285: 26581-98 (2010) Article DOI: 10.1074/jbc.M110.113951 BindingDB Entry DOI: 10.7270/Q2XD1083
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM92516 (RF 00032, 12) Show SMILES Cc1cc(C)c(C#N)c(OC(=O)c2cccs2)n1 Show InChI InChI=1S/C13H10N2O2S/c1-8-6-9(2)15-12(10(8)7-14)17-13(16)11-4-3-5-18-11/h3-6H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	740	n/a	3.47E+3	n/a	n/a	n/a	n/a	6.5	n/a
Ecole Polytechnique Fédérale de Lausanne					Assay Description The assay principle is based on measuring the absorbance of D-dopachrome methyl ester (red), which is transformed by enzymatically active MIF to the ...				J Biol Chem 285: 26581-98 (2010) Article DOI: 10.1074/jbc.M110.113951 BindingDB Entry DOI: 10.7270/Q2XD1083
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50240520 ((isothiocyanatomethyl)benzene | BITC, 17 | Benzyls...) Show SMILES S=C=NCc1ccccc1 Show InChI InChI=1S/C8H7NS/c10-7-9-6-8-4-2-1-3-5-8/h1-5H,6H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	790	n/a	6.50E+3	n/a	n/a	n/a	n/a	6.5	n/a
Ecole Polytechnique Fédérale de Lausanne					Assay Description The assay principle is based on measuring the absorbance of D-dopachrome methyl ester (red), which is transformed by enzymatically active MIF to the ...				J Biol Chem 285: 26581-98 (2010) Article DOI: 10.1074/jbc.M110.113951 BindingDB Entry DOI: 10.7270/Q2XD1083
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM92506 (BTB 09588, 1) Show SMILES [O-][N+](=O)c1ccc(ONC(=O)c2cccs2)c(c1)[N+]([O-])=O Show InChI InChI=1S/C11H7N3O6S/c15-11(10-2-1-5-21-10)12-20-9-4-3-7(13(16)17)6-8(9)14(18)19/h1-6H,(H,12,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	860	n/a	2.45E+3	n/a	n/a	n/a	n/a	6.5	n/a
Ecole Polytechnique Fédérale de Lausanne					Assay Description The assay principle is based on measuring the absorbance of D-dopachrome methyl ester (red), which is transformed by enzymatically active MIF to the ...				J Biol Chem 285: 26581-98 (2010) Article DOI: 10.1074/jbc.M110.113951 BindingDB Entry DOI: 10.7270/Q2XD1083
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM32847 ((5,5-dimethyl-3-oxidanylidene-cyclohexen-1-yl) 4-c...) Show SMILES CC1(C)CC(=O)C=C(C1)OC(=O)c1ccc(Cl)cc1 |c:6| Show InChI InChI=1S/C15H15ClO3/c1-15(2)8-12(17)7-13(9-15)19-14(18)10-3-5-11(16)6-4-10/h3-7H,8-9H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.30E+3	n/a	3.31E+3	n/a	n/a	n/a	n/a	6.5	n/a
Ecole Polytechnique Fédérale de Lausanne					Assay Description The assay principle is based on measuring the absorbance of D-dopachrome methyl ester (red), which is transformed by enzymatically active MIF to the ...				J Biol Chem 285: 26581-98 (2010) Article DOI: 10.1074/jbc.M110.113951 BindingDB Entry DOI: 10.7270/Q2XD1083
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM92510 (JFD 03186, 6) Show SMILES Cc1ccc(cc1)C(=O)OC1=CC(=O)c2ccccc2C1=O |t:11| Show InChI InChI=1S/C18H12O4/c1-11-6-8-12(9-7-11)18(21)22-16-10-15(19)13-4-2-3-5-14(13)17(16)20/h2-10H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.58E+3	n/a	1.95E+3	n/a	n/a	n/a	n/a	6.5	n/a
Ecole Polytechnique Fédérale de Lausanne					Assay Description The assay principle is based on measuring the absorbance of D-dopachrome methyl ester (red), which is transformed by enzymatically active MIF to the ...				J Biol Chem 285: 26581-98 (2010) Article DOI: 10.1074/jbc.M110.113951 BindingDB Entry DOI: 10.7270/Q2XD1083
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM92513 (ML 00144, 9) Show SMILES Oc1ccc(C=NNC(=O)NN=Cc2ccc(O)cc2)cc1 |w:5.4,11.10| Show InChI InChI=1S/C15H14N4O3/c20-13-5-1-11(2-6-13)9-16-18-15(22)19-17-10-12-3-7-14(21)8-4-12/h1-10,20-21H,(H2,18,19,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.81E+3	n/a	1.70E+4	n/a	n/a	n/a	n/a	6.5	n/a
Ecole Polytechnique Fédérale de Lausanne					Assay Description The assay principle is based on measuring the absorbance of D-dopachrome methyl ester (red), which is transformed by enzymatically active MIF to the ...				J Biol Chem 285: 26581-98 (2010) Article DOI: 10.1074/jbc.M110.113951 BindingDB Entry DOI: 10.7270/Q2XD1083
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM92508 (DP 00477, 3) Show SMILES FC(F)(F)c1cccc(NC(=O)C(C#N)C(=S)Nc2ccccc2Cl)c1 Show InChI InChI=1S/C17H11ClF3N3OS/c18-13-6-1-2-7-14(13)24-16(26)12(9-22)15(25)23-11-5-3-4-10(8-11)17(19,20)21/h1-8,12H,(H,23,25)(H,24,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	1.84E+3	n/a	3.31E+4	n/a	n/a	n/a	n/a	6.5	n/a
Ecole Polytechnique Fédérale de Lausanne					Assay Description The assay principle is based on measuring the absorbance of D-dopachrome methyl ester (red), which is transformed by enzymatically active MIF to the ...				J Biol Chem 285: 26581-98 (2010) Article DOI: 10.1074/jbc.M110.113951 BindingDB Entry DOI: 10.7270/Q2XD1083
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM92507 (DFP 00129, 2) Show SMILES [O-][N+](=O)c1cc(cs1)C(=O)NC(=S)Nc1ccccc1Cl Show InChI InChI=1S/C12H9ClN3O3S2/c13-8-3-1-2-4-9(8)14-12(20)15-11(17)7-5-10(16(18)19)21-6-7/h1-5H,6H2,(H2,14,15,17,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	2.47E+3	n/a	7.08E+3	n/a	n/a	n/a	n/a	6.5	n/a
Ecole Polytechnique Fédérale de Lausanne					Assay Description The assay principle is based on measuring the absorbance of D-dopachrome methyl ester (red), which is transformed by enzymatically active MIF to the ...				J Biol Chem 285: 26581-98 (2010) Article DOI: 10.1074/jbc.M110.113951 BindingDB Entry DOI: 10.7270/Q2XD1083
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM92509 (HTS 11308, 4) Show SMILES CC(=O)N1CCSC1C(=O)NNC(=O)c1ccc2OCOc2c1 Show InChI InChI=1S/C14H15N3O5S/c1-8(18)17-4-5-23-14(17)13(20)16-15-12(19)9-2-3-10-11(6-9)22-7-21-10/h2-3,6,14H,4-5,7H2,1H3,(H,15,19)(H,16,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	2.85E+3	n/a	4.57E+3	n/a	n/a	n/a	n/a	6.5	n/a
Ecole Polytechnique Fédérale de Lausanne					Assay Description The assay principle is based on measuring the absorbance of D-dopachrome methyl ester (red), which is transformed by enzymatically active MIF to the ...				J Biol Chem 285: 26581-98 (2010) Article DOI: 10.1074/jbc.M110.113951 BindingDB Entry DOI: 10.7270/Q2XD1083
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM92517 (RJC 02246, 13) Show SMILES O=C(C(C#N)C1Nc2ccccc2S1)c1ccco1 Show InChI InChI=1S/C14H10N2O2S/c15-8-9(13(17)11-5-3-7-18-11)14-16-10-4-1-2-6-12(10)19-14/h1-7,9,14,16H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.31E+3	n/a	1.51E+4	n/a	n/a	n/a	n/a	6.5	n/a
Ecole Polytechnique Fédérale de Lausanne					Assay Description The assay principle is based on measuring the absorbance of D-dopachrome methyl ester (red), which is transformed by enzymatically active MIF to the ...				J Biol Chem 285: 26581-98 (2010) Article DOI: 10.1074/jbc.M110.113951 BindingDB Entry DOI: 10.7270/Q2XD1083
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM31712 (HEXACHLOROPHENE | Hexach-lorophene | MLS000028433 ...) Show SMILES Oc1c(Cl)cc(Cl)c(Cl)c1Cc1c(O)c(Cl)cc(Cl)c1Cl Show InChI InChI=1S/C13H6Cl6O2/c14-6-2-8(16)12(20)4(10(6)18)1-5-11(19)7(15)3-9(17)13(5)21/h2-3,20-21H,1H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.55E+3	n/a	6.00E+3	n/a	n/a	n/a	n/a	6.5	n/a
Ecole Polytechnique Fédérale de Lausanne					Assay Description The assay principle is based on measuring the absorbance of D-dopachrome methyl ester (red), which is transformed by enzymatically active MIF to the ...				J Biol Chem 285: 26581-98 (2010) Article DOI: 10.1074/jbc.M110.113951 BindingDB Entry DOI: 10.7270/Q2XD1083
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50326574 (6-phenylpyridazin-3-yl thiophene-2-carboxylate | C...) Show SMILES O=C(Oc1ccc(nn1)-c1ccccc1)c1cccs1 Show InChI InChI=1S/C15H10N2O2S/c18-15(13-7-4-10-20-13)19-14-9-8-12(16-17-14)11-5-2-1-3-6-11/h1-10H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergent				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50326574 (6-phenylpyridazin-3-yl thiophene-2-carboxylate | C...) Show SMILES O=C(Oc1ccc(nn1)-c1ccccc1)c1cccs1 Show InChI InChI=1S/C15H10N2O2S/c18-15(13-7-4-10-20-13)19-14-9-8-12(16-17-14)11-5-2-1-3-6-11/h1-10H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM33627 ((1,3-benzoxazol-2-ylthio)formic acid butyl ester |...) Show SMILES CCCCOC(=O)Sc1nc2ccccc2o1 Show InChI InChI=1S/C12H13NO3S/c1-2-3-8-15-12(14)17-11-13-9-6-4-5-7-10(9)16-11/h4-7H,2-3,8H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM33627 ((1,3-benzoxazol-2-ylthio)formic acid butyl ester |...) Show SMILES CCCCOC(=O)Sc1nc2ccccc2o1 Show InChI InChI=1S/C12H13NO3S/c1-2-3-8-15-12(14)17-11-13-9-6-4-5-7-10(9)16-11/h4-7H,2-3,8H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergent				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50326573 (1-Phenyl-3-(2-thiazolyl)-2-thiourea | 1-phenyl-3-(...) Show SMILES S=C(Nc1nncs1)Nc1ccccc1 Show InChI InChI=1S/C9H8N4S2/c14-8(12-9-13-10-6-15-9)11-7-4-2-1-3-5-7/h1-6H,(H2,11,12,13,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50326573 (1-Phenyl-3-(2-thiazolyl)-2-thiourea | 1-phenyl-3-(...) Show SMILES S=C(Nc1nncs1)Nc1ccccc1 Show InChI InChI=1S/C9H8N4S2/c14-8(12-9-13-10-6-15-9)11-7-4-2-1-3-5-7/h1-6H,(H2,11,12,13,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergent				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM47541 (1-(2-chlorophenyl)-3-(2-pyridinyl)thiourea | 1-(2-...) Show SMILES Clc1ccccc1NC(=S)Nc1ccccn1 Show InChI InChI=1S/C12H10ClN3S/c13-9-5-1-2-6-10(9)15-12(17)16-11-7-3-4-8-14-11/h1-8H,(H2,14,15,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergent				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM47541 (1-(2-chlorophenyl)-3-(2-pyridinyl)thiourea | 1-(2-...) Show SMILES Clc1ccccc1NC(=S)Nc1ccccn1 Show InChI InChI=1S/C12H10ClN3S/c13-9-5-1-2-6-10(9)15-12(17)16-11-7-3-4-8-14-11/h1-8H,(H2,14,15,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50326572 (CHEMBL1253383 | N-(2-bromobenzoyloxy)-4-chlorobenz...) Show SMILES Clc1ccc(cc1)C(=O)NOC(=O)c1ccccc1Br Show InChI InChI=1S/C14H9BrClNO3/c15-12-4-2-1-3-11(12)14(19)20-17-13(18)9-5-7-10(16)8-6-9/h1-8H,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM92512 (KM 05004, 8) Show SMILES FC(F)(F)c1cccc(c1)C(=O)OC1=C(Cl)C(=O)CCC1 |c:14| Show InChI InChI=1S/C14H10ClF3O3/c15-12-10(19)5-2-6-11(12)21-13(20)8-3-1-4-9(7-8)14(16,17)18/h1,3-4,7H,2,5-6H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.02E+3	n/a	n/a	n/a	n/a	6.5	n/a
Ecole Polytechnique Fédérale de Lausanne					Assay Description The assay principle is based on measuring the absorbance of D-dopachrome methyl ester (red), which is transformed by enzymatically active MIF to the ...				J Biol Chem 285: 26581-98 (2010) Article DOI: 10.1074/jbc.M110.113951 BindingDB Entry DOI: 10.7270/Q2XD1083
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50326572 (CHEMBL1253383 | N-(2-bromobenzoyloxy)-4-chlorobenz...) Show SMILES Clc1ccc(cc1)C(=O)NOC(=O)c1ccccc1Br Show InChI InChI=1S/C14H9BrClNO3/c15-12-4-2-1-3-11(12)14(19)20-17-13(18)9-5-7-10(16)8-6-9/h1-8H,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergent				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50326570 ((1H-benzo[d][1,2,3]triazol-1-yl)(2-methoxyphenyl)m...) Show SMILES COc1ccccc1C(=O)n1nnc2ccccc12 Show InChI InChI=1S/C14H11N3O2/c1-19-13-9-5-2-6-10(13)14(18)17-12-8-4-3-7-11(12)15-16-17/h2-9H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50326571 (5-(2-nitro-4-(trifluoromethylsulfonyl)phenylthio)-...) Show SMILES [O-][N+](=O)c1cc(ccc1Sc1nnc(S)s1)S(=O)(=O)C(F)(F)F Show InChI InChI=1S/C9H4F3N3O4S4/c10-9(11,12)23(18,19)4-1-2-6(5(3-4)15(16)17)21-8-14-13-7(20)22-8/h1-3H,(H,13,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50326570 ((1H-benzo[d][1,2,3]triazol-1-yl)(2-methoxyphenyl)m...) Show SMILES COc1ccccc1C(=O)n1nnc2ccccc12 Show InChI InChI=1S/C14H11N3O2/c1-19-13-9-5-2-6-10(13)14(18)17-12-8-4-3-7-11(12)15-16-17/h2-9H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergent				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM92514 (NRB 04242, 10) Show SMILES COc1ccc(cc1)C(=O)\C=C\OC(=C)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H15ClO3/c1-13(14-3-7-16(19)8-4-14)22-12-11-18(20)15-5-9-17(21-2)10-6-15/h3-12H,1H2,2H3/b12-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.48E+4	n/a	n/a	n/a	n/a	6.5	n/a
Ecole Polytechnique Fédérale de Lausanne					Assay Description The assay principle is based on measuring the absorbance of D-dopachrome methyl ester (red), which is transformed by enzymatically active MIF to the ...				J Biol Chem 285: 26581-98 (2010) Article DOI: 10.1074/jbc.M110.113951 BindingDB Entry DOI: 10.7270/Q2XD1083
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50326569 (CHEMBL1253492 | methyl 2-(4-methyl-5-(thiophen-2-y...) Show SMILES COC(=O)CSc1nnc(-c2cccs2)n1C Show InChI InChI=1S/C10H11N3O2S2/c1-13-9(7-4-3-5-16-7)11-12-10(13)17-6-8(14)15-2/h3-5H,6H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.86E+4	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50326569 (CHEMBL1253492 | methyl 2-(4-methyl-5-(thiophen-2-y...) Show SMILES COC(=O)CSc1nnc(-c2cccs2)n1C Show InChI InChI=1S/C10H11N3O2S2/c1-13-9(7-4-3-5-16-7)11-12-10(13)17-6-8(14)15-2/h3-5H,6H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergent				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50096008 (3-Acetyl-7-hydroxy-chromen-2-one | 3-acetyl-7-hydr...) Show SMILES CC(=O)c1cc2ccc(O)cc2oc1=O Show InChI InChI=1S/C11H8O4/c1-6(12)9-4-7-2-3-8(13)5-10(7)15-11(9)14/h2-5,13H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50326576 (3-(2,4-difluorophenylamino)-1-(5-methylfuran-2-yl)...) Show SMILES Cc1ccc(o1)C(=O)CC=Nc1ccc(F)cc1F |w:9.9| Show InChI InChI=1S/C14H11F2NO2/c1-9-2-5-14(19-9)13(18)6-7-17-12-4-3-10(15)8-11(12)16/h2-5,7-8H,6H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50326568 (CHEMBL1253493 | N-(furan-2-ylmethyl)-7-nitrobenzo[...) Show SMILES [O-][N+](=O)c1ccc(NCc2ccco2)c2nonc12 Show InChI InChI=1S/C11H8N4O4/c16-15(17)9-4-3-8(10-11(9)14-19-13-10)12-6-7-2-1-5-18-7/h1-5,12H,6H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50326567 (CHEMBL1253544 | ethyl 2-cyano-3-(2,4-dihydroxyphen...) Show SMILES CCOC(=O)C(=C\c1ccc(O)cc1O)\C#N Show InChI InChI=1S/C12H11NO4/c1-2-17-12(16)9(7-13)5-8-3-4-10(14)6-11(8)15/h3-6,14-15H,2H2,1H3/b9-5+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM52230 ((Z)-2-(1,3-benzoxazol-2-yl)-3-(2-pyridinylamino)-2...) Show SMILES O=CC(C=Nc1ccccn1)c1nc2ccccc2o1 |w:4.4| Show InChI InChI=1S/C15H11N3O2/c19-10-11(9-17-14-7-3-4-8-16-14)15-18-12-5-1-2-6-13(12)20-15/h1-11H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50096008 (3-Acetyl-7-hydroxy-chromen-2-one | 3-acetyl-7-hydr...) Show SMILES CC(=O)c1cc2ccc(O)cc2oc1=O Show InChI InChI=1S/C11H8O4/c1-6(12)9-4-7-2-3-8(13)5-10(7)15-11(9)14/h2-5,13H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.03E+5	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergent				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50326567 (CHEMBL1253544 | ethyl 2-cyano-3-(2,4-dihydroxyphen...) Show SMILES CCOC(=O)C(=C\c1ccc(O)cc1O)\C#N Show InChI InChI=1S/C12H11NO4/c1-2-17-12(16)9(7-13)5-8-3-4-10(14)6-11(8)15/h3-6,14-15H,2H2,1H3/b9-5+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergent				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50326577 (3-nitroso-2-phenylindolizine | CHEMBL1253586) Show SMILES O=Nc1c(cc2ccccn12)-c1ccccc1 Show InChI InChI=1S/C14H10N2O/c17-15-14-13(11-6-2-1-3-7-11)10-12-8-4-5-9-16(12)14/h1-10H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.21E+5	n/a	n/a	n/a	n/a	n/a	n/a
Brain Mind Institute Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity				Bioorg Med Chem 18: 5425-40 (2010) Article DOI: 10.1016/j.bmc.2010.05.010 BindingDB Entry DOI: 10.7270/Q2KH0P9C
					More data for this Ligand-Target Pair