| Reaction Details |
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 | Report a problem with these data |
| Target | Macrophage migration inhibitory factor |
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| Ligand | BDBM50240520 |
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| Substrate/Competitor | BDBM92519 |
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| Meas. Tech. | Tautomerase Enzyme Assay |
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| pH | 6.5±0 |
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| Ki | 7.9e+2±n/a nM |
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| IC50 | 6.50e+3±n/a nM |
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| Citation |  Ouertatani-Sakouhi, H; El-Turk, F; Fauvet, B; Cho, MK; Pinar Karpinar, D; Le Roy, D; Dewor, M; Roger, T; Bernhagen, J; Calandra, T; Zweckstetter, M; Lashuel, HA Identification and characterization of novel classes of macrophage migration inhibitory factor (MIF) inhibitors with distinct mechanisms of action. J Biol Chem285:26581-98 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Macrophage migration inhibitory factor |
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| Name: | Macrophage migration inhibitory factor |
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| Synonyms: | GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase |
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| Type: | Enzyme |
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| Mol. Mass.: | 12478.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14174 |
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| Residue: | 115 |
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| Sequence: | MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALC
SLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
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| BDBM50240520 |
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| BDBM92519 |
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| Name | BDBM50240520 |
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| Synonyms: | (isothiocyanatomethyl)benzene | BITC, 17 | Benzylsenfoel | CHEMBL55285 | Isothiocyanic acid, benzyl ester | alpha-isothiocyanatotoluene | benzyl isothiocyanate |
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| Type | Small organic molecule |
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| Emp. Form. | C8H7NS |
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| Mol. Mass. | 149.213 |
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| SMILES | S=C=NCc1ccccc1 |
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| Structure | 
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