| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Casein kinase I isoform alpha |
|---|
| Ligand | BDBM50011236 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Enzyme Assay |
|---|
| pH | 7.4±0 |
|---|
| Temperature | 303.15±0 K |
|---|
| IC50 | 1.10e+5±n/a nM |
|---|
| Citation |  Chijiwa, T; Hagiwara, M; Hidaka, H A newly synthesized selective casein kinase I inhibitor, N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide, and affinity purification of casein kinase I from bovine testis. J Biol Chem264:4924-7 (1989) [PubMed] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Casein kinase I isoform alpha |
|---|
| Name: | Casein kinase I isoform alpha |
|---|
| Synonyms: | CK1 | CKI-alpha | CSNK1A1 | Casein Kinase I | Casein kinase 1 alpha (CK1 alpha) | Casein kinase I isoform alpha/delta | KC1A_HUMAN |
|---|
| Type: | Serine/threonine-protein kinase |
|---|
| Mol. Mass.: | 38936.59 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P48729 |
|---|
| Residue: | 337 |
|---|
| Sequence: | MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE
SKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN
LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK
MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTM
LKQKAAQQAASSSGQGQQAQTPTGKQTDKTKSNMKGF
|
|
|
|---|
| BDBM50011236 |
|---|
| n/a |
|---|
| Name | BDBM50011236 |
|---|
| Synonyms: | CHEMBL344314 | Isoquinoline-5-sulfonic acid (2-amino-ethyl)-amide | Isoquinolinesulfonamide, H-9 | N-(2-aminoethyl)isoquinoline-5-sulfonamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H13N3O2S |
|---|
| Mol. Mass. | 251.305 |
|---|
| SMILES | NCCNS(=O)(=O)c1cccc2cnccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
