| Reaction Details |
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 | Report a problem with these data |
| Target | Thiamine-binding periplasmic protein |
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| Ligand | BDBM92962 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Titration Assay |
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| Kd | 7.4±0.7 nM |
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| Citation |  Soriano, EV; Rajashankar, KR; Hanes, JW; Bale, S; Begley, TP; Ealick, SE Structural similarities between thiamin-binding protein and thiaminase-I suggest a common ancestor. Biochemistry47:1346-57 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thiamine-binding periplasmic protein |
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| Name: | Thiamine-binding periplasmic protein |
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| Synonyms: | THIB_ECOLI | tbpA | thiB | yabL |
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| Type: | Protein |
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| Mol. Mass.: | 36163.97 |
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| Organism: | Escherichia coli (strain K12) |
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| Description: | P31550 |
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| Residue: | 327 |
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| Sequence: | MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPVVKKAFEADCNCELKLVALEDG
VSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSGVAADAVNVPGGWNNDTFVPF
DYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYQDPRTSTPGLGLLLWMQKVYGDDAP
QAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTSPAYHILEEKKDNYAAANFSEGH
YLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIPTGNWMYPVANVTLPAGFEKLTKPA
TTLEFTPAEVAAQRQAWISEWQRAVSR
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| BDBM92962 |
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| n/a |
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| Name | BDBM92962 |
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| Synonyms: | ThDP |
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| Type | Small molecule |
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| Emp. Form. | C12H19N4O7P2S |
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| Mol. Mass. | 425.314 |
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| SMILES | Cc1c(CCOP(O)(=O)OP(O)(O)=O)sc[n+]1Cc1cnc(C)nc1N |
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| Structure | 
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