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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Activated CDC42 kinase 1 | ||
| Ligand | BDBM98459 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | AlphaScreen Assay | ||
| IC50 | 175.9±n/a nM | ||
| Citation |  Crew, AP; Jin, M; Kadalbajoo, M; Kleinberg, A; Mulvihill, MJ; Wang, J Substituted imidazopyr- and imidazotri-azines US Patent US8481733 Publication Date 7/9/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Activated CDC42 kinase 1 | |||
| Name: | Activated CDC42 kinase 1 | ||
| Synonyms: | ACK1 | ACK1_HUMAN | Activated CDC42 kinase 1 (ACK-1) | TNK2 | Tyrosine kinase non-receptor protein 2 | ||
| Type: | Protein | ||
| Mol. Mass.: | 114577.86 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q07912 | ||
| Residue: | 1038 | ||
| Sequence: |
| ||
| BDBM98459 | |||
| n/a | |||
| Name | BDBM98459 | ||
| Synonyms: | US8481733, 271 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H26N6O | ||
| Mol. Mass. | 414.5028 | ||
| SMILES | NC[C@H]1CC[C@@H](CC1)c1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnn12 |r,wU:5.8,wD:2.1,(-.46,-8.88,;.63,-7.79,;.23,-6.31,;1.32,-5.22,;.92,-3.73,;-.56,-3.33,;-1.65,-4.42,;-1.25,-5.91,;-.96,-1.84,;-.06,-.6,;-.96,.65,;-.56,2.14,;.92,2.53,;1.32,4.02,;.23,5.11,;.63,6.6,;2.12,7,;3.21,5.91,;4.7,6.31,;5.09,7.79,;4.01,8.88,;2.52,8.48,;-1.25,4.71,;-1.65,3.22,;-2.43,.17,;-3.76,.94,;-3.76,2.48,;-5.09,.17,;-5.09,-1.37,;-3.76,-2.14,;-2.43,-1.37,)| | ||
| Structure | 
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