| Reaction Details |
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 | Report a problem with these data |
| Target | Macrophage colony-stimulating factor 1 receptor |
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| Ligand | BDBM98625 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence Polarization Competition Assay |
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| pH | 7.5±0 |
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| IC50 | 2.7±n/a nM |
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| Citation |  Illig, CR; Chen, J; Meegalia, SK; Wall, MJ Inhibitors of c-fms kinase US Patent US8497376 Publication Date 7/30/2013 |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Macrophage colony-stimulating factor 1 receptor |
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| Name: | Macrophage colony-stimulating factor 1 receptor |
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| Synonyms: | CSF1R_MOUSE | Csf1r | Csfmr | Fms | Macrophage colony-stimulating factor 1 receptor | Macrophage colony-stimulating factor 1 receptor (c-Fms) | Proto-oncogene c-Fms |
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| Type: | Protein |
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| Mol. Mass.: | 109173.45 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P09581 |
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| Residue: | 977 |
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| Sequence: | MELGPPLVLLLATVWHGQGAPVIEPSGPELVVEPGETVTLRCVSNGSVEWDGPISPYWTL
DPESPGSTLTTRNATFKNTGTYRCTELEDPMAGSTTIHLYVKDPAHSWNLLAQEVTVVEG
QEAVLPCLITDPALKDSVSLMREGGRQVLRKTVYFFSPWRGFIIRKAKVLDSNTYVCKTM
VNGRESTSTGIWLKVNRVHPEPPQIKLEPSKLVRIRGEAAQIVCSATNAEVGFNVILKRG
DTKLEIPLNSDFQDNYYKKVRALSLNAVDFQDAGIYSCVASNDVGTRTATMNFQVVESAY
LNLTSEQSLLQEVSVGDSLILTVHADAYPSIQHYNWTYLGPFFEDQRKLEFITQRAIYRY
TFKLFLNRVKASEAGQYFLMAQNKAGWNNLTFELTLRYPPEVSVTWMPVNGSDVLFCDVS
GYPQPSVTWMECRGHTDRCDEAQALQVWNDTHPEVLSQKPFDKVIIQSQLPIGTLKHNMT
YFCKTHNSVGNSSQYFRAVSLGQSKQLPDESLFTPVVVACMSVMSLLVLLLLLLLYKYKQ
KPKYQVRWKIIERYEGNSYTFIDPTQLPYNEKWEFPRNNLQFGKTLGAGAFGKVVEATAF
GLGKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVI
TEYCCYGDLLNFLRRKAEAMLGPSLSPGQDSEGDSSYKNIHLEKKYVRRDSGFSSQGVDT
YVEMRPVSTSSSDSFFKQDLDKEASRPLELWDLLHFSSQVAQGMAFLASKNCIHRDVAAR
NVLLTSGHVAKIGDFGLARDIMNDSNYVVKGNARLPVKWMAPESIFDCVYTVQSDVWSYG
ILLWEIFSLGLNPYPGILVNNKFYKLVKDGYQMAQPVFAPKNIYSIMQSCWDLEPTRRPT
FQQICFLLQEQARLERRDQDYANLPSSGGSSGSDSGGGSSGGSSSEPEEESSSEHLACCE
PGDIAQPLLQPNNYQFC
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| BDBM98625 |
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| n/a |
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| Name | BDBM98625 |
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| Synonyms: | US8497376, 6 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H38N4O4 |
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| Mol. Mass. | 518.6471 |
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| SMILES | COC[C@@]12CC[C@@](COC)(C[C@H](C1)c1ccc(NC(=O)c3ncc([nH]3)C#N)c(c1)C1=CCC(C)(C)CC1)O2 |r,t:32| |
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| Structure | 
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