| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM98861 |
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| Substrate/Competitor | BDBM98856 |
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| Meas. Tech. | Spectrophotometric Assay |
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| IC50 | 1.1±0.0 nM |
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| Citation |  Blizzard, TA; Chen, H; Gude, C; Hermes, JD; Imbriglio, J; Kim, S; Wu, JY; Mortko, CJ; Mangion, I; Rivera, N; Ruck, RT; Shevlin, M Beta-lactamase inhibitors US Patent US8487093 Publication Date 7/16/2013 |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | Beta-lactamase (AmpC) |
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| Type: | Enzyme |
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| Mol. Mass.: | 43489.98 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | Q3LG62 |
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| Residue: | 397 |
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| Sequence: | MRDTRFPCLCGIAASTLLFATTPAIADEAPADRLKALVDAAVQPVMKANDIPGLAVAISL
KGEPHYFSYGLASKEDGRRVTPETLFEIGSVSKTFTVTLAGYALAQDKMRLDDRASQHWP
ALQGSRFDGISLLDLATYTAGGLPLQFPDSVQKDQAQIRDYYRQWQPTYAPGSQRLYSNP
SIGLFGYLAARSLGQPFERLMEQQLFPALGLEQTHLDVPEAALAQYAQGYGKDDRPLRVG
PGPLDAEGYGVKTSAADLLRFVDANLHPERLDRPWAQALDATHRGYYKVGDMTQGLGWEA
YDWPISLKRLQAGNSTPMALQPHRIARLPAPQALEGQRLLNKTGSTNGFGAYVAFVPGRD
LGLVILANRNYPNAERVKIAYAILSGLEQQAKVPLKR
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| BDBM98861 |
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| BDBM98856 |
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| Name | BDBM98861 |
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| Synonyms: | US8487093, 7 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H16N4O7S |
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| Mol. Mass. | 372.354 |
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| SMILES | COc1cc(NC(=O)[C@@H]2CCC3CN2C(=O)N3OS(O)(=O)=O)ccn1 |r| |
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| Structure | 
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