| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM98831 |
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| Substrate/Competitor | BDBM98856 |
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| Meas. Tech. | Spectrophotometric Assay |
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| IC50 | 4±0.0 nM |
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| Citation |  Blizzard, TA; Chen, H; Gude, C; Hermes, JD; Imbriglio, J; Kim, S; Wu, JY; Mortko, CJ; Mangion, I; Rivera, N; Ruck, RT; Shevlin, M Beta-lactamase inhibitors US Patent US8487093 Publication Date 7/16/2013 |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | Beta-lactamase (KPC-2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 27537.23 |
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| Organism: | Klebsiella pneumoniae |
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| Description: | I7AKP2 |
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| Residue: | 260 |
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| Sequence: | ATALTNLVAEPFAKLEQDFGGSIGVYAMDTGSGATVSYRAEERFPLCSSFKGFLAAAVLA
RSQQQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKEL
GGPAGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAP
QRQQFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGVYGTANDYAVVWPTGRAPIVLAV
YTRAPNKDDKYSEAVIAAAA
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| BDBM98831 |
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| BDBM98856 |
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| Name | BDBM98831 |
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| Synonyms: | US8487093, 236 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H18FN3O7S |
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| Mol. Mass. | 367.351 |
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| SMILES | OS(=O)(=O)ON1[C@H]2CN([C@@H](CC2)C(=O)O[C@H]2CCNC[C@@H]2F)C1=O |r| |
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| Structure | 
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