| Reaction Details |
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 | Report a problem with these data |
| Target | Monoacylglycerol lipase ABHD2 |
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| Ligand | BDBM280509 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Competitive Activity-Based Protein Profiling |
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| IC50 | >1000±n/a nM |
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| Citation |  Cisar, JS; Grice, CA; Jones, TK; Weber, OD; Buzard, DJ; Shaghafi, MB Spirocycle compounds and methods of making and using same US Patent US10030020 Publication Date 7/24/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Monoacylglycerol lipase ABHD2 |
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| Name: | Monoacylglycerol lipase ABHD2 |
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| Synonyms: | 2-arachidonoylglycerol hydrolase | ABHD2_MOUSE | Abhd2 | Abhydrolase domain-containing protein 2 | Labh-2 | Labh2 | Lung alpha/beta hydrolase 2 | MmLABH2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 48378.90 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | n/a |
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| Residue: | 425 |
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| Sequence: | MNAMLETPELPAVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPDLYFQDSGLSRFLLKSCP
LLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITMSDGATSTFDLFEPLAEH
CVGDDITMVICPGIANHSEKQYIRTFVDYAQKNGYRCAVLNHLGALPNIELTSPRMFTYG
CTWEFGAMVNYIKRTYPQTQLVVVGFSLGGNIVCKYLGETQANQEKVLCCVSVCQGYSAL
RAQETFMQWDQCRRFYNFLMADNMKKIILSHRQALFGDHVKKPQSLEDTDLSRLYTATSL
MQIDDNVMRKFHGYNSLKEYYEEESCMRYLHRIYVPLMLVNAADDPLVHESLLTIPKSLS
EKRENVMFVLPLHGGHLGFFEGSVLFPEPLTWMDKLVVEYANAICQWERNKSQCSDTEQM
EAELE
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| BDBM280509 |
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| n/a |
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| Name | BDBM280509 |
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| Synonyms: | US10030020, Example 54 | US10781211, Example 54 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H32ClF6N3O3 |
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| Mol. Mass. | 571.983 |
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| SMILES | CC1(C)CC2(CN1Cc1cccc(Cl)c1N1CCOCC1)CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F |
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| Structure | 
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