| Reaction Details |
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 | Report a problem with these data |
| Target | Sodium- and chloride-dependent glycine transporter 1 |
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| Ligand | BDBM100975 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Uptake Inhibition Assay |
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| Temperature | 273.15±n/a K |
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| IC50 | 62.5±n/a nM |
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| Citation |  Kolczewski, S; Pinard, E Tetrahydro-pyran derivatives US Patent US8524909 Publication Date 9/3/2013 |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Sodium- and chloride-dependent glycine transporter 1 |
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| Name: | Sodium- and chloride-dependent glycine transporter 1 |
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| Synonyms: | Glycine transporter 1b | SC6A9_BOVIN | SLC6A9 |
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| Type: | Protein |
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| Mol. Mass.: | 71324.09 |
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| Organism: | Bos taurus (Bovine) |
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| Description: | Q28039 |
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| Residue: | 638 |
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| Sequence: | MAAAQGPVAPSSLEQNGAVPSEATKKDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPY
LCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVV
STYIGIYYNVVICIAFYYFFSSMTPVLPWTYCNNPWNTPDCMSVLDNPNITNGSQPPALP
GNVSQALNQTLKRTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWVVVFLCLIRG
VKSSGKVVYFTATFPYVVLTILFIRGVTLEGAFTGIMYYLTPQWDKILEAKVWGDAASQI
FYSLGCAWGGLVTMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVD
VSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEV
GNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVIISCIMCVSIM
YIYGHQNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILIFSVIQYQPITYNQYQYPSW
RVRIGFLMALSSVICIPLYALFQFCRTDGDTLLHRLKNATKPSRDWGPALLEHRTRRYAP
TTTPSPEDGLEVQPLHPDKAQIPMVGSNGSSRFQDSRI
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| BDBM100975 |
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| n/a |
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| Name | BDBM100975 |
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| Synonyms: | US8524909, 57 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H27F3N2O3 |
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| Mol. Mass. | 412.4459 |
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| SMILES | COc1cc(cc(C2CC2)c1C(=O)N[C@H]1COCC[C@@H]1N1CCCC1)C(F)(F)F |r| |
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| Structure | 
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