Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Corticotropin-releasing factor receptor 1 | ||
| Ligand | BDBM101719 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Binding Assay | ||
| IC50 | 47±0.0 nM | ||
| Citation |  Shin, K; Terauchi, T; Takahashi, Y; Hashizume, M; Takeda, K; Shikata, K; Inomata, A Pyrazolothiazole compound US Patent US8530504 Publication Date 9/10/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Corticotropin-releasing factor receptor 1 | |||
| Name: | Corticotropin-releasing factor receptor 1 | ||
| Synonyms: | CRF-R | CRF-R2 Alpha | CRF1 | CRFR | CRFR1 | CRFR1_HUMAN | CRH-R 1 | CRHR | CRHR1 | Corticotropin releasing factor receptor 1 | Corticotropin-releasing factor receptor 1 (CRF-1) | Corticotropin-releasing factor receptor 1 (CRF1) | Corticotropin-releasing hormone receptor 1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50744.31 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34998 | ||
| Residue: | 444 | ||
| Sequence: |
| ||
| BDBM101719 | |||
| n/a | |||
| Name | BDBM101719 | ||
| Synonyms: | US8530504, 83 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H37N3O5S | ||
| Mol. Mass. | 503.654 | ||
| SMILES | CCCCN(C1CCOCC1)c1c(OCC)nn2c(csc12)-c1c(OC)cc(COC)cc1OC |(3.49,5.75,;2,6.15,;.91,5.06,;-.57,5.46,;-1.66,4.37,;-3.15,4.77,;-4.24,3.68,;-5.73,4.08,;-6.13,5.56,;-5.04,6.65,;-3.55,6.25,;-1.27,2.88,;-2.17,1.63,;-3.71,1.63,;-4.48,.3,;-6.02,.3,;-1.27,.39,;.2,.86,;1.66,.39,;2.57,1.63,;1.66,2.88,;.2,2.4,;2.06,-1.1,;.97,-2.19,;-.51,-1.79,;-1.6,-2.88,;1.37,-3.68,;2.86,-4.08,;3.26,-5.56,;2.17,-6.65,;.68,-6.25,;3.95,-2.99,;3.55,-1.5,;4.64,-.41,;6.13,-.81,)| | ||
| Structure | 
| ||