| Reaction Details |
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 | Report a problem with these data |
| Target | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial |
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| Ligand | BDBM101777 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | 1.0e+2±n/a nM |
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| Citation |  Fukuoka, M; Yokogawa, T; Miyahara, S; Miyakoshi, H; Yano, W; Taguchi, J; Takao, Y Uracil compound or salt thereof having human deoxyuridine triphosphatase inhibitory activity US Patent US8530490 Publication Date 9/10/2013 |
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| More Info.: | Get all data from this article, Assay Method |
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| Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial |
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| Name: | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial |
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| Synonyms: | DUT | DUT_HUMAN | Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) | Deoxyuridine triphosphatase (dUTPase) | dUTP pyrophosphatase |
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| Type: | Enzyme |
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| Mol. Mass.: | 26574.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P33316 |
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| Residue: | 252 |
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| Sequence: | MTPLCPRPALCYHFLTSLLRSAMQNARGARQRAEAAVLSGPGPPLGRAAQHGIPRPLSSA
GRLSQGCRGASTVGAAGWKGELPKAGGSPAPGPETPAISPSKRARPAEVGGMQLRFARLS
EHATAPTRGSARAAGYDLYSAYDYTIPPMEKAVVKTDIQIALPSGCYGRVAPRSGLAAKH
FIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERIFYPEIEEVQALDDTE
RGSGGFGSTGKN
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| BDBM101777 |
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| n/a |
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| Name | BDBM101777 |
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| Synonyms: | US8530490, 37 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H27F2N3O6S |
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| Mol. Mass. | 535.56 |
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| SMILES | Fc1ccc(cc1)[C@@H](NS(=O)(=O)CCCOCn1ccc(=O)[nH]c1=O)c1ccc(F)c(OCC2CC2)c1 |r| |
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| Structure | 
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