Reaction Details |
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Target | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial |
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Ligand | BDBM50190553 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Inhibition Assay |
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IC50 | 1.85e+5±n/a nM |
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Citation | Fukuoka, M; Yokogawa, T; Miyahara, S; Miyakoshi, H; Yano, W; Taguchi, J; Takao, Y Uracil compound or salt thereof having human deoxyuridine triphosphatase inhibitory activity US Patent US8530490 Publication Date 9/10/2013 |
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More Info.: | Get all data from this article, Assay Method |
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Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial |
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Name: | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial |
Synonyms: | DUT | DUT_HUMAN | Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) | Deoxyuridine triphosphatase (dUTPase) | dUTP pyrophosphatase |
Type: | Enzyme |
Mol. Mass.: | 26574.03 |
Organism: | Homo sapiens (Human) |
Description: | P33316 |
Residue: | 252 |
Sequence: | MTPLCPRPALCYHFLTSLLRSAMQNARGARQRAEAAVLSGPGPPLGRAAQHGIPRPLSSA
GRLSQGCRGASTVGAAGWKGELPKAGGSPAPGPETPAISPSKRARPAEVGGMQLRFARLS
EHATAPTRGSARAAGYDLYSAYDYTIPPMEKAVVKTDIQIALPSGCYGRVAPRSGLAAKH
FIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERIFYPEIEEVQALDDTE
RGSGGFGSTGKN
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BDBM50190553 |
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n/a |
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Name | BDBM50190553 |
Synonyms: | 1-[2-(trityloxy)ethoxymethyl]uracil | CHEMBL424704 | US8530490, Comparative 1 |
Type | Small organic molecule |
Emp. Form. | C26H24N2O4 |
Mol. Mass. | 428.4798 |
SMILES | O=c1ccn(COCCOC(c2ccccc2)(c2ccccc2)c2ccccc2)c(=O)[nH]1 |
Structure |
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