| Reaction Details |
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 | Report a problem with these data |
| Target | Orexin receptor type 2 |
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| Ligand | BDBM102178 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | FLIPR Assay |
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| pH | 7.4±0 |
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| Ki | 39±n/a nM |
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| Citation |  Badiger, S; Behnke, D; Betschart, C; Chaudhari, V; Cotesta, S; Hinrichs, JH; Ofner, S; Pandit, C; Wagner, J Diaza-spiro[5.5]undecanes US Patent US8530648 Publication Date 9/10/2013 |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Orexin receptor type 2 |
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| Name: | Orexin receptor type 2 |
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| Synonyms: | HCRTR2 | Hypocretin receptor type 2 | OX2R_HUMAN | Orexin receptor type 2 (OR 2) | Orexin receptor type 2 (OR-2) | Orexin receptor type 2 (OX2) | Orexin receptor type 2 (OX2R) | Orexin receptor type 2 (OxR2) | Ox-2-R | Ox2-R |
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| Type: | Protein |
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| Mol. Mass.: | 50710.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O43614 |
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| Residue: | 444 |
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| Sequence: | MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARR
KTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAAN
PIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKL
SEQVVLTSISTLPAANGAGPLQNW
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| BDBM102178 |
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| n/a |
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| Name | BDBM102178 |
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| Synonyms: | US8530648, 111 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H27N7O |
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| Mol. Mass. | 453.5389 |
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| SMILES | O=C1N(Cc2ccccc2-n2nccn2)CCCC11CCN(CC1)c1cnc2ccccc2n1 |
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| Structure | 
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