| Reaction Details |
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 | Report a problem with these data |
| Target | Egl nine homolog 1 |
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| Ligand | BDBM102348 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Assay |
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| IC50 | 1.4e+4±n/a nM |
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| Citation |  Gardner, JH; Shalwitz, R Prolyl hydroxylase inhibitors US Patent US8536181 Publication Date 9/17/2013 |
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| More Info.: | Get all data from this article, Assay Method |
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| Egl nine homolog 1 |
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| Name: | Egl nine homolog 1 |
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| Synonyms: | C1orf12 | EGLN1 | EGLN1_HUMAN | Egl nine homolog 1 (EGLN1) | Hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PH2) | Hypoxia-inducible factor prolyl hydroxylase 2 (HIFPH2) | Prolyl hydroxylase domain-containing protein 2 (PHD2) |
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| Type: | Protein |
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| Mol. Mass.: | 46035.59 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9GZT9 |
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| Residue: | 426 |
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| Sequence: | MANDSGGPGGPSPSERDRQYCELCGKMENLLRCSRCRSSFYCCKEHQRQDWKKHKLVCQG
SEGALGHGVGPHQHSGPAPPAAVPPPRAGAREPRKAAARRDNASGDAAKGKVKAKPPADP
AAAASPCRAAAGGQGSAVAAEAEPGKEEPPARSSLFQEKANLYPPSNTPGDALSPGGGLR
PNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQL
VSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCNGKLGSYKINGRTKAMV
ACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKF
DRLLFFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVKYLTGEKGVRVELNKPSDS
VGKDVF
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| BDBM102348 |
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| n/a |
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| Name | BDBM102348 |
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| Synonyms: | US10562854, No. A41 | US8536181, A41 | US9278930, A41 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H28ClN3O4 |
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| Mol. Mass. | 433.928 |
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| SMILES | CC(C)(C)OC(=O)N1CCN(Cc2ccn(Cc3ccc(Cl)cc3)c(=O)c2O)CC1 |
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| Structure | 
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