| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM102402 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Binding Assay |
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| Temperature | 298.15±0 K |
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| Ki | 2.7±0.0 nM |
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| Citation |  Inagaki, M; Hara, S; Haga, N; Tamura, Y; Goto, Y; Hasegawa, T 6,7-unsaturated-7-carbamoyl substituted morphinan derivative US Patent US8536192 Publication Date 9/17/2013 |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44503.11 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor. |
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| Residue: | 398 |
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| Sequence: | MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM102402 |
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| n/a |
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| Name | BDBM102402 |
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| Synonyms: | US8536192, I-122 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H27ClN2O7S |
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| Mol. Mass. | 559.03 |
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| SMILES | OC1=C(C[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45)C(=O)NS(=O)(=O)c1cccc(Cl)c1 |r,t:1,THB:20:19:4:24.8.7| |
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| Structure | 
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