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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 3 | ||
| Ligand | BDBM102501 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Kinase Assay | ||
| IC50 | 530±0.0 nM | ||
| Citation |  Furet, P; Graus Porta, D; Guagnano, V Quinoxaline carboxamide derivatives as protein tyrosine kinase inhibitors US Patent US8536175 Publication Date 9/17/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 3 | |||
| Name: | Fibroblast growth factor receptor 3 | ||
| Synonyms: | CD_antigen: CD333 | FGFR-3 | FGFR3 | FGFR3_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 3 (FGFR3) | JTK4 | ||
| Type: | Protein | ||
| Mol. Mass.: | 87699.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22607 | ||
| Residue: | 806 | ||
| Sequence: |
| ||
| BDBM102501 | |||
| n/a | |||
| Name | BDBM102501 | ||
| Synonyms: | US8536175, 2 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C29H29Cl2N5O3 | ||
| Mol. Mass. | 566.478 | ||
| SMILES | CCN1CCN(CC1)c1cccc(NC(=O)c2ccc(-c3c(Cl)c(OC)cc(OC)c3Cl)c3nccnc23)c1 |(-10.01,4.67,;-8.47,4.67,;-7.7,3.33,;-6.16,3.33,;-5.39,2,;-6.16,.67,;-7.7,.67,;-8.47,2,;-5.39,-.67,;-6.16,-2,;-5.39,-3.33,;-3.85,-3.33,;-3.08,-2,;-1.54,-2,;-.77,-.67,;-1.54,.67,;.77,-.67,;1.54,.67,;3.08,.67,;3.85,-.67,;5.39,-.67,;6.16,-2,;5.39,-3.33,;7.7,-2,;8.47,-3.33,;10.01,-3.33,;8.47,-.67,;7.7,.67,;8.47,2,;7.7,3.33,;6.16,.67,;5.39,2,;3.08,-2,;3.85,-3.33,;3.08,-4.67,;1.54,-4.67,;.77,-3.33,;1.54,-2,;-3.85,-.67,)| | ||
| Structure | 
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