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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 3 | ||
| Ligand | BDBM102524 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Kinase Assay | ||
| IC50 | 2550±0.0 nM | ||
| Citation |  Furet, P; Graus Porta, D; Guagnano, V Quinoxaline carboxamide derivatives as protein tyrosine kinase inhibitors US Patent US8536175 Publication Date 9/17/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 3 | |||
| Name: | Fibroblast growth factor receptor 3 | ||
| Synonyms: | CD_antigen: CD333 | FGFR-3 | FGFR3 | FGFR3_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 3 (FGFR3) | JTK4 | ||
| Type: | Protein | ||
| Mol. Mass.: | 87699.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22607 | ||
| Residue: | 806 | ||
| Sequence: |
| ||
| BDBM102524 | |||
| n/a | |||
| Name | BDBM102524 | ||
| Synonyms: | US8536175, 86 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H28Cl2N6O3 | ||
| Mol. Mass. | 555.456 | ||
| SMILES | COc1cc(OC)c(Cl)c(c1Cl)-c1ccc(C(=O)Nc2ccccn2)c2ncc(nc12)N(C)CCN(C)C |(8.09,-.67,;6.55,-.67,;5.78,.67,;6.55,2,;5.78,3.33,;6.55,4.67,;5.78,6,;4.23,3.33,;3.47,4.67,;3.47,2,;4.23,.67,;3.47,-.67,;1.93,2,;1.15,3.33,;-.38,3.33,;-1.15,2,;-2.69,2,;-3.47,3.33,;-3.47,.67,;-5,.67,;-5.78,2,;-7.31,2,;-8.08,.67,;-7.31,-.67,;-5.78,-.67,;-.38,.67,;-1.15,-.67,;-.38,-2,;1.15,-2,;1.93,-.67,;1.15,.67,;1.92,-3.33,;1.15,-4.67,;3.46,-3.33,;4.23,-4.67,;5.77,-4.67,;6.54,-6,;6.54,-3.33,)| | ||
| Structure | 
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