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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 3 | ||
| Ligand | BDBM102526 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Kinase Assay | ||
| IC50 | 7±0.0 nM | ||
| Citation |  Furet, P; Graus Porta, D; Guagnano, V Quinoxaline carboxamide derivatives as protein tyrosine kinase inhibitors US Patent US8536175 Publication Date 9/17/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 3 | |||
| Name: | Fibroblast growth factor receptor 3 | ||
| Synonyms: | CD_antigen: CD333 | FGFR-3 | FGFR3 | FGFR3_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 3 (FGFR3) | JTK4 | ||
| Type: | Protein | ||
| Mol. Mass.: | 87699.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22607 | ||
| Residue: | 806 | ||
| Sequence: |
| ||
| BDBM102526 | |||
| n/a | |||
| Name | BDBM102526 | ||
| Synonyms: | US8536175, 93 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H24F2N6O3 | ||
| Mol. Mass. | 494.4933 | ||
| SMILES | COc1cc(OC)c(F)c(c1F)-c1ccc(C(=O)Nc2ncc(CN3CCCC3)[nH]2)c2nccnc12 |(10.25,-2.72,;8.71,-2.72,;7.94,-1.38,;8.71,-.05,;7.94,1.28,;8.71,2.62,;7.94,3.95,;6.4,1.28,;5.63,2.62,;5.63,-.05,;6.4,-1.38,;5.63,-2.72,;4.09,-.05,;3.32,1.28,;1.78,1.28,;1.01,-.05,;-.53,-.05,;-1.3,1.28,;-1.3,-1.38,;-2.84,-1.38,;-3.74,-.14,;-5.21,-.61,;-5.21,-2.15,;-6.54,-2.92,;-7.88,-2.15,;-8.35,-.69,;-9.89,-.69,;-10.37,-2.15,;-9.12,-3.06,;-3.74,-2.63,;1.78,-1.38,;1.01,-2.72,;1.78,-4.05,;3.32,-4.05,;4.09,-2.72,;3.32,-1.38,)| | ||
| Structure | 
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