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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 3 | ||
| Ligand | BDBM102540 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Kinase Assay | ||
| IC50 | 7±0.0 nM | ||
| Citation |  Furet, P; Graus Porta, D; Guagnano, V Quinoxaline carboxamide derivatives as protein tyrosine kinase inhibitors US Patent US8536175 Publication Date 9/17/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 3 | |||
| Name: | Fibroblast growth factor receptor 3 | ||
| Synonyms: | CD_antigen: CD333 | FGFR-3 | FGFR3 | FGFR3_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 3 (FGFR3) | JTK4 | ||
| Type: | Protein | ||
| Mol. Mass.: | 87699.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22607 | ||
| Residue: | 806 | ||
| Sequence: |
| ||
| BDBM102540 | |||
| n/a | |||
| Name | BDBM102540 | ||
| Synonyms: | US8536175, 144 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H28ClFN6O3 | ||
| Mol. Mass. | 551.012 | ||
| SMILES | COc1cc(OC)c(Cl)c(c1F)-c1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)cn2)c2nccnc12 |(8.07,3.99,;8.84,2.66,;8.07,1.32,;8.84,-.01,;8.07,-1.34,;8.84,-2.68,;10.38,-2.68,;6.53,-1.34,;5.76,-2.68,;5.76,-.01,;6.53,1.32,;5.76,2.66,;4.22,-.01,;3.45,1.32,;1.91,1.32,;1.14,-.01,;-.4,-.01,;-1.17,1.32,;-1.17,-1.34,;-2.71,-1.34,;-3.48,-.01,;-5.02,-.01,;-5.79,-1.34,;-7.33,-1.34,;-8.1,-.01,;-9.64,-.01,;-10.41,1.32,;-9.64,2.66,;-10.41,3.99,;-8.1,2.66,;-7.33,1.32,;-5.02,-2.68,;-3.48,-2.68,;1.91,-1.34,;1.14,-2.68,;1.91,-4.01,;3.45,-4.01,;4.22,-2.68,;3.45,-1.34,)| | ||
| Structure | 
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