Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 3 | ||
| Ligand | BDBM102549 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Kinase Assay | ||
| IC50 | 9±0 nM | ||
| Citation |  Furet, P; Graus Porta, D; Guagnano, V Quinoxaline carboxamide derivatives as protein tyrosine kinase inhibitors US Patent US8536175 Publication Date 9/17/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 3 | |||
| Name: | Fibroblast growth factor receptor 3 | ||
| Synonyms: | CD_antigen: CD333 | FGFR-3 | FGFR3 | FGFR3_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 3 (FGFR3) | JTK4 | ||
| Type: | Protein | ||
| Mol. Mass.: | 87699.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22607 | ||
| Residue: | 806 | ||
| Sequence: |
| ||
| BDBM102549 | |||
| n/a | |||
| Name | BDBM102549 | ||
| Synonyms: | US8536175, 175 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H23F2N5O3 | ||
| Mol. Mass. | 467.4679 | ||
| SMILES | COc1cc(OC)c(F)c(c1F)-c1ccc(C(=O)Nc2ncc(CN(C)C)[nH]2)c2ncccc12 |(9.73,-2.67,;8.19,-2.67,;7.42,-1.34,;8.19,-0,;7.42,1.33,;8.19,2.66,;7.42,4,;5.88,1.33,;5.11,2.66,;5.11,-0,;5.88,-1.34,;5.11,-2.67,;3.57,-0,;2.8,1.33,;1.26,1.33,;.49,-0,;-1.05,-0,;-1.82,1.33,;-1.82,-1.34,;-3.36,-1.34,;-4.27,-.09,;-5.73,-.57,;-5.73,-2.11,;-7.07,-2.88,;-8.4,-2.11,;-9.74,-2.88,;-8.4,-.57,;-4.27,-2.58,;1.26,-1.34,;.49,-2.67,;1.26,-4.01,;2.8,-4.01,;3.57,-2.67,;2.8,-1.34,)| | ||
| Structure | 
| ||