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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cathepsin K | ||
| Ligand | BDBM103352 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | In Vitro Inhibition Assay | ||
| Ki | >4800±0.0 nM | ||
| Citation |  Quibell, M; Watts, JP; Flinn, NS Furo[3, 2-B] pyrrol-3-ones as cathespin S inhibitors US Patent US8552202 Publication Date 10/8/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cathepsin K | |||
| Name: | Cathepsin K | ||
| Synonyms: | CATK_HUMAN | CTSK | CTSO | CTSO2 | Cathepsin O | Cathepsin O2 | Cathepsin X | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 36975.68 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P43235 | ||
| Residue: | 329 | ||
| Sequence: |
| ||
| BDBM103352 | |||
| n/a | |||
| Name | BDBM103352 | ||
| Synonyms: | US8552202, Compound 4 | ||
| Type | Small organic molecules | ||
| Emp. Form. | C22H28N2O4 | ||
| Mol. Mass. | 384.4687 | ||
| SMILES | C[C@H]1CCC(CC1)[C@H](NC(=O)c1ccccc1)C(=O)N1CC[C@H]2OCC(=O)[C@@H]12 |r,wU:7.8,27.29,22.24,wD:1.0,(.08,4.62,;.08,3.08,;-1.25,2.31,;-1.25,.77,;.08,,;1.42,.77,;1.42,2.31,;.08,-1.54,;-1.25,-2.31,;-2.58,-1.54,;-2.58,,;-3.92,-2.31,;-5.25,-1.54,;-6.59,-2.31,;-6.59,-3.85,;-5.25,-4.62,;-3.92,-3.85,;1.42,-2.31,;1.42,-3.85,;2.75,-1.54,;2.75,,;4.22,.48,;5.12,-.77,;6.59,-1.25,;6.59,-2.79,;5.12,-3.26,;4.35,-4.6,;4.22,-2.02,)| | ||
| Structure | 
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