Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | Complement C1r subcomponent | ||
Ligand | BDBM108108 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Inhibition Assay | ||
Ki | >30000±0.0 nM | ||
Citation | Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A Trypsin-like serine protease inhibitors, and their preparation and use US Patent US8598206 Publication Date 12/3/2013 | ||
More Info.: | Get all data from this article, Assay Method | ||
Complement C1r subcomponent | |||
Name: | Complement C1r subcomponent | ||
Synonyms: | C1R | C1R_HUMAN | Complement C1r | Complement C1r subcomponent | ||
Type: | Enzyme | ||
Mol. Mass.: | 80113.65 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P00736 | ||
Residue: | 705 | ||
Sequence: |
| ||
BDBM108108 | |||
n/a | |||
Name | BDBM108108 | ||
Synonyms: | US8598206, 117 | US8598206, 123 | ||
Type | Small organic molecule | ||
Emp. Form. | C34H46N7O5S | ||
Mol. Mass. | 664.838 | ||
SMILES | NC(=N)c1ccc(CNC(=O)[C@H](CCC2CCNCC2)NC(=O)[C@@H](CCCC2=CC=[N](O)C=C2)NS(=O)(=O)Cc2ccccc2)cc1 |r,wU:23.35,11.20,c:33,t:28,30,(11.34,1.93,;10,2.7,;10,4.23,;8.67,1.93,;8.67,.38,;7.34,-.38,;6,.38,;4.67,-.38,;3.33,.38,;2,-.38,;2,-1.93,;.67,.38,;.67,1.93,;2,2.69,;2,4.23,;3.33,5,;3.33,6.54,;2,7.31,;.67,6.54,;.67,5,;-.67,-.38,;-2,.38,;-2,1.93,;-3.33,-.38,;-3.33,-1.93,;-2,-2.69,;-2,-4.23,;-.67,-5,;-.67,-6.54,;.67,-7.31,;2,-6.54,;3.33,-7.31,;2,-5,;.67,-4.23,;-4.67,.38,;-6,-.38,;-6.77,-1.72,;-5.23,-1.72,;-7.34,.38,;-8.67,-.38,;-10,.38,;-11.34,-.38,;-11.34,-1.93,;-10,-2.69,;-8.67,-1.93,;6,1.93,;7.34,2.69,)| | ||
Structure |