| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Procathepsin L |
|---|
| Ligand | BDBM110196 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Cathepsin L Inhibition Assay |
|---|
| pH | 5.5±n/a |
|---|
| Temperature | 310.15±n/a K |
|---|
| IC50 | >1.00e+5±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Baek, KH; Karki, R; Lee, ES; Na, Y; Kwon, Y Synthesis and investigation of dihydroxychalcones as calpain and cathepsin inhibitors. Bioorg Chem51:24-30 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Procathepsin L |
|---|
| Name: | Procathepsin L |
|---|
| Synonyms: | CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 37557.19 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Purchased from Calbiochem (San Diego, CA). |
|---|
| Residue: | 333 |
|---|
| Sequence: | MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
|
|
|
|---|
| BDBM110196 |
|---|
| n/a |
|---|
| Name | BDBM110196 |
|---|
| Synonyms: | 1-(3,5-Dihydroxyphenyl)-3-(thiophen-3-yl)propenone (23) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H10O3S |
|---|
| Mol. Mass. | 246.282 |
|---|
| SMILES | Oc1cc(O)cc(c1)C(=O)\C=C\c1ccsc1 |
|---|
| Structure | 
|
|---|
Search and Browse
