| Reaction Details |
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 | Report a problem with these data |
| Target | PC4 and SFRS1-interacting protein |
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| Ligand | BDBM61326 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | TR-FRET-based biochemical high throughput dose response assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration |
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| IC50 | 176.9±n/a nM |
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| Citation |  PubChem, PC TR-FRET-based biochemical high throughput dose response assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration PubChem Bioassay(2014)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| PC4 and SFRS1-interacting protein |
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| Name: | PC4 and SFRS1-interacting protein |
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| Synonyms: | DFS70 | LEDGF | LEDGF/p75 | PSIP1 | PSIP1_HUMAN | PSIP2 | lens epithelium-derived growth factor p75 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 60120.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_6708281 |
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| Residue: | 530 |
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| Sequence: | MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFP
YSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKE
DTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKR
GRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKE
EDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRR
NMLKGQHEKEAADRKRKQEEQMETEQQNKDEGKKPEVKKVEKKRETSMDSRLQRIHAEIK
NSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLY
NKFKNMFLVGEGDSVITQVLNKSLAEQRQHEEANKTKDQGKKGPNKKLEKEQTGSKTLNG
GSDAQDGNQPQHNGESNEDSKDNHEASTKKKPSSEERETEISLKDSTLDN
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| BDBM61326 |
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| n/a |
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| Name | BDBM61326 |
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| Synonyms: | 1-N',2-N'-bis[(E)-(2-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]ethanedihydrazide | MLS000974661 | N'~1~,N'~2~-bis(2,4-dihydroxybenzylidene)ethanedihydrazide | N1',N2'-bis[(E)-(2-hydroxy-4-keto-cyclohexa-2,5-dien-1-ylidene)methyl]oxalohydrazide | N1',N2'-bis[(E)-(2-hydroxy-4-oxo-1-cyclohexa-2,5-dienylidene)methyl]ethanedihydrazide | N1',N2'-bis[(E)-(2-oxidanyl-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene)methyl]ethanedihydrazide | SMR000496526 | cid_6508451 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H14N4O6 |
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| Mol. Mass. | 358.3056 |
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| SMILES | Oc1ccc(C=NNC(=O)C(=O)NN=Cc2ccc(O)cc2O)c(O)c1 |w:6.6,13.12| |
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| Structure | 
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