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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | ||
| Ligand | BDBM50378639 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Inhibition Assay | ||
| pH | 7.5±n/a | ||
| IC50 | 66.4±n/a nM | ||
| Comments | extracted | ||
| Citation |  Cho, H; Wu, Y; Choi, C Thiazolidinedione derivative and use thereof US Patent US8637558 Publication Date 1/28/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | |||
| Name: | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | ||
| Synonyms: | 15-PGDH | 15-hydroxyprostaglandin dehydrogenase [NAD+] | HPGD | PGDH1 | PGDH_HUMAN | Prostaglandin dehydrogenase 1 (15-PGDH) | SDR36C1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 28974.46 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P15428 | ||
| Residue: | 266 | ||
| Sequence: |
| ||
| BDBM50378639 | |||
| n/a | |||
| Name | BDBM50378639 | ||
| Synonyms: | CHEMBL599018 | US8637558, 37 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H21NO3S | ||
| Mol. Mass. | 331.429 | ||
| SMILES | CC1CCC(COc2ccc(C=C3SC(O)=NC3=O)cc2)CC1 |w:11.10,c:15,(4.23,-1.81,;3.51,-1.4,;3.51,-.57,;2.8,-.16,;2.08,-.57,;1.37,-.16,;.65,-.57,;-.06,-.16,;-.06,.67,;-.78,1.08,;-1.49,.67,;-2.2,1.08,;-2.92,.67,;-3.01,-.15,;-3.81,-.33,;-4.15,-1.08,;-4.23,.39,;-3.67,1,;-3.84,1.81,;-1.49,-.16,;-.78,-.57,;2.08,-1.4,;2.8,-1.81,)| | ||
| Structure | 
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