| Reaction Details |
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 | Report a problem with these data |
| Target | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] |
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| Ligand | BDBM50049243 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| pH | 7.5±n/a |
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| IC50 | 1739.1±n/a nM |
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| Comments | extracted |
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| Citation |  Cho, H; Wu, Y; Choi, C Thiazolidinedione derivative and use thereof US Patent US8637558 Publication Date 1/28/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] |
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| Name: | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] |
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| Synonyms: | 15-PGDH | 15-hydroxyprostaglandin dehydrogenase [NAD+] | HPGD | PGDH1 | PGDH_HUMAN | Prostaglandin dehydrogenase 1 (15-PGDH) | SDR36C1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 28974.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P15428 |
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| Residue: | 266 |
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| Sequence: | MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF
IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLD
YMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNA
ICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNG
AIMKITTSKGIHFQDYDTTPFQAKTQ
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| BDBM50049243 |
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| n/a |
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| Name | BDBM50049243 |
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| Synonyms: | 5-[4-(1-Methyl-cyclohexylmethoxy)-benzyl]-thiazolidine-2,4-dione | 5-[4-(1-Methyl-cyclohexylmethoxy)-benzyl]-thiazolidine-2,4-dione (ciglitazone) | 5-[4-(1-Methyl-cyclohexylmethoxy)-benzyl]-thiazolidine-2,4-dione(Ciglitazone) | CHEMBL7002 | CIGLITAZONE | US8637558, 112 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H23NO3S |
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| Mol. Mass. | 333.445 |
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| SMILES | CC1(COc2ccc(Cc3sc(=O)[nH]c3O)cc2)CCCCC1 |
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| Structure | 
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