| Reaction Details |
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 | Report a problem with these data |
| Target | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] |
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| Ligand | BDBM118091 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| pH | 7.5±n/a |
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| IC50 | 1079.8±n/a nM |
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| Comments | extracted |
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| Citation |  Cho, H; Wu, Y; Choi, C Thiazolidinedione derivative and use thereof US Patent US8637558 Publication Date 1/28/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] |
|---|
| Name: | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] |
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| Synonyms: | 15-PGDH | 15-hydroxyprostaglandin dehydrogenase [NAD+] | HPGD | PGDH1 | PGDH_HUMAN | Prostaglandin dehydrogenase 1 (15-PGDH) | SDR36C1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 28974.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P15428 |
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| Residue: | 266 |
|---|
| Sequence: | MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF
IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLD
YMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNA
ICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNG
AIMKITTSKGIHFQDYDTTPFQAKTQ
|
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|
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| BDBM118091 |
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| n/a |
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| Name | BDBM118091 |
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| Synonyms: | US8637558, 129 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H19NO3S |
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| Mol. Mass. | 389.467 |
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| SMILES | Oc1[nH]c(=O)sc1Cc1ccc(OCc2ccc(cc2)-c2ccccc2)cc1 |
|---|
| Structure | 
|
|---|
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